Professor Chris Goodnow FAA FRS is Executive Director of the Garvan Institute of Medical Research, holds The Bill and Patricia Ritchie Foundation Chair as Head of the Immunogenomics Laboratory at Garvan, and is Professor and Director of the Cellular Genomics Futures Institute at UNSW Sydney. Chris trained in veterinary medicine and surgery, immunochemistry, and immunology at the University of Sydney and in DNA technology and molecular immunology at Stanford University. Chris is internationally recognised for discovering and establishing the concept of sequential tolerance checkpoints to prevent the immune system attacking “self” while fighting off “foreign” infections, laying the scientific foundation for the recent success of checkpoint inhibitor drugs to activate immune destruction of “self” cancer cells. He pioneered the use of mammalian genome sequencing to reveal how the body’s phenotype results from its’ genotype – “phenomics”. Most recently his team have used single cell genomics to discover that rogue immune cells bypass tolerance checkpoints to cause autoimmune disease through mutation pathways that also cause lymphoma and leukemia. Chris’ many awards include the AAI Pharmingen Award, Gottschalk Medal, Health Minister’s Prize, Centenary Medal, Ramaciotti Medal, GSK Award for Research Excellence, William E. Paul Award, Fellow of the Australian Academy of Science, Fellow of the Royal Society, and Member of the US National Academy of Sciences.
Journal articles
add
Rouet R; Henry JY; Johansen MD; Sobti M; Balachandran H; Langley DB; Walker GJ; Lenthall H; Jackson J; Ubiparipovic S; Mazigi O; Schofield P; Burnett DL; Brown SHJ; Martinello M; Hudson B; Gilroy N; Post JJ; Kelleher A; Jäck HM; Goodnow CC; Turville SG; Rawlinson WD; Bull RA; Stewart AG; Hansbro PM; Christ D, 2023, 'Broadly neutralizing SARS-CoV-2 antibodies through epitope-based selection from convalescent patients', Nature Communications, 14, pp. 687, http://dx.doi.org/10.1038/s41467-023-36295-5
2023
Khoo WH; Jackson K; Phetsouphanh C; Zaunders JJ; Alquicira-Hernandez J; Yazar S; Ruiz-Diaz S; Singh M; Dhenni R; Kyaw W; Tea F; Merheb V; Lee FXZ; Burrell R; Howard-Jones A; Koirala A; Zhou L; Yuksel A; Catchpoole DR; Lai CL; Vitagliano TL; Rouet R; Christ D; Tang B; West NP; George S; Gerrard J; Croucher PI; Kelleher AD; Goodnow CG; Sprent JD; Powell JE; Brilot F; Nanan R; Hsu PS; Deenick EK; Britton PN; Phan TG, 2023, 'Tracking the clonal dynamics of SARS-CoV-2-specific T cells in children and adults with mild/asymptomatic COVID-19', Clinical Immunology, 246, pp. 109209, http://dx.doi.org/10.1016/j.clim.2022.109209
2023
Masle-Farquhar E; Jeelall Y; White J; Bier J; Deenick EK; Brink R; Horikawa K; Goodnow CC, 2023, 'CARD11 gain-of-function mutation drives cell-autonomous accumulation of PD-1+ ICOShigh activated T cells, T-follicular, T-regulatory and T-follicular regulatory cells', Frontiers in Immunology, 14, http://dx.doi.org/10.3389/fimmu.2023.1095257
2023
Logan GJ; Mietzsch M; Khandekar N; D'Silva A; Anderson D; Mandwie M; Hsi J; Nelson AR; Chipman P; Jackson J; Schofield P; Christ D; Goodnow CC; Reed JH; Farrar MA; McKenna R; Alexander IE, 2023, 'Structural and functional characterization of capsid binding by anti-AAV9 monoclonal antibodies from infants after SMA gene therapy', Molecular Therapy, http://dx.doi.org/10.1016/j.ymthe.2023.03.032
2023
Aggarwal A; Stella AO; Walker G; Akerman A; Esneau C; Milogiannakis V; Burnett DL; McAllery S; Silva MR; Lu Y; Foster CSP; Brilot F; Pillay A; Van Hal S; Mathivanan V; Fichter C; Kindinger A; Hoppe AC; Munier ML; Amatayakul-Chantler S; Roth N; Coppola G; Symonds GP; Schofield P; Jackson J; Lenthall H; Henry JY; Mazigi O; Jäck HM; Davenport MP; Darley DR; Matthews GV; Khoury DS; Cromer D; Goodnow CC; Christ D; Robosa R; Starck DJ; Bartlett NW; Rawlinson WD; Kelleher AD; Turville SG, 2022, 'Platform for isolation and characterization of SARS-CoV-2 variants enables rapid characterization of Omicron in Australia', Nature Microbiology, 7, pp. 896 - 908, http://dx.doi.org/10.1038/s41564-022-01135-7
2022
Ho WHJ; Law AMK; Masle-Farquhar E; Castillo LE; Mawson A; O’Bryan MK; Goodnow CC; Gallego-Ortega D; Oakes SR; Ormandy CJ, 2022, 'Activation of the viral sensor oligoadenylate synthetase 2 (Oas2) prevents pregnancy-driven mammary cancer metastases', Breast Cancer Research, 24, pp. 31, http://dx.doi.org/10.1186/s13058-022-01525-z
2022
Yang R; Avery DT; Jackson KJL; Ogishi M; Benhsaien I; Du L; Ye X; Han J; Rosain J; Peel JN; Alyanakian MA; Neven B; Winter S; Puel A; Boisson B; Payne KJ; Wong M; Russell AJ; Mizoguchi Y; Okada S; Uzel G; Goodnow CC; Latour S; Bakkouri JE; Bousfiha A; Preece K; Gray PE; Keller B; Warnatz K; Boisson-Dupuis S; Abel L; Pan-Hammarström Q; Bustamante J; Ma CS; Casanova JL; Tangye SG, 2022, 'Human T-bet governs the generation of a distinct subset of CD11chighCD21low B cells', Science Immunology, 7, pp. eabq3277, http://dx.doi.org/10.1126/sciimmunol.abq3277
2022
Pelham SJ; Caldirola MS; Avery DT; Mackie J; Rao G; Gothe F; Peters TJ; Guerin A; Neumann D; Vokurkova D; Hwa V; Zhang W; Lyu SC; Chang I; Manohar M; Nadeau KC; Gaillard MI; Bezrodnik L; Iotova V; Zwirner NW; Gutierrez M; Al-Herz W; Goodnow CC; Vargas-Hernández A; Forbes Satter LR; Hambleton S; Deenick EK; Ma CS; Tangye SG, 2022, 'STAT5B restrains human B-cell differentiation to maintain humoral immune homeostasis', Journal of Allergy and Clinical Immunology, 150, pp. 931 - 946, http://dx.doi.org/10.1016/j.jaci.2022.04.011
2022
Schulz SR; Hoffmann M; Roth E; Pracht K; Burnett DL; Mazigi O; Schuh W; Manger B; Mielenz D; Goodnow CC; Christ D; Pöhlmann S; Jäck HM, 2022, 'Augmented neutralization of SARS-CoV-2 Omicron variant by boost vaccination and monoclonal antibodies', European Journal of Immunology, 52, pp. 970 - 977, http://dx.doi.org/10.1002/eji.202249841
2022
Langley DB; Schofield P; Nevoltris D; Jackson J; Jackson KJL; Peters TJ; Burk M; Matthews JM; Basten A; Goodnow CC; van Nunen S; Reed JH; Christ D, 2022, 'Genetic and structural basis of the human anti-α-galactosyl antibody response', Proceedings of the National Academy of Sciences of the United States of America, 119, pp. e2123212119, http://dx.doi.org/10.1073/pnas.2123212119
2022
Masle-Farquhar E; Peters TJ; Miosge LA; Parish IA; Weigel C; Oakes CC; Reed JH; Goodnow CC, 2022, 'Uncontrolled CD21low age-associated and B1 B cell accumulation caused by failure of an EGR2/3 tolerance checkpoint', Cell Reports, 38, http://dx.doi.org/10.1016/j.celrep.2021.110259
2022
Nüssing S; Miosge LA; Lee K; Olshansky M; Barugahare A; Roots CM; Sontani Y; Day EB; Koutsakos M; Kedzierska K; Goodnow CC; Russ BE; Daley SR; Turner SJ, 2022, 'SATB1 ensures appropriate transcriptional programs within naïve CD8+ T cells', Immunology and Cell Biology, 100, pp. 636 - 652, http://dx.doi.org/10.1111/imcb.12566
2022
Masle-Farquhar E; Jackson KJL; Peters TJ; Al-Eryani G; Singh M; Payne KJ; Rao G; Avery DT; Apps G; Kingham J; Jara CJ; Skvortsova K; Swarbrick A; Ma CS; Suan D; Uzel G; Chua I; Leiding JW; Heiskanen K; Preece K; Kainulainen L; O'Sullivan M; Cooper MA; Seppänen MRJ; Mustjoki S; Brothers S; Vogel TP; Brink R; Tangye SG; Reed JH; Goodnow CC, 2022, 'STAT3 gain-of-function mutations connect leukemia with autoimmune disease by pathological NKG2Dhi CD8+ T cell dysregulation and accumulation', Immunity, 55, pp. 2386 - 2404.e8, http://dx.doi.org/10.1016/j.immuni.2022.11.001
2022
Rouet R; Mazigi O; Walker GJ; Langley DB; Sobti M; Schofield P; Lenthall H; Jackson J; Ubiparipovic S; Henry JY; Abayasingam A; Burnett D; Kelleher A; Brink R; Bull RA; Turville S; Stewart AG; Goodnow CC; Rawlinson WD; Christ D, 2021, 'Potent SARS-CoV-2 binding and neutralization through maturation of iconic SARS-CoV-1 antibodies', mAbs, 13, pp. 1922134, http://dx.doi.org/10.1080/19420862.2021.1922134
2021
Boast B; Helian K; Andrews D; Li X; Cho V; Closa A; Sutton H; Reed J; Bergmann H; Roots C; Yabas M; Barthel N; Omari S; Young C; Miosge L; Eyras E; Nutt S; Hein N; Hannan K; Cockburn I; Goodnow C; Enders A, 2021, 'Dysregulation of PAX5 causes uncommitted B cell development and tumorigenesis in mice', , http://dx.doi.org/10.1101/2021.01.29.428877
2021
Wirasinha RC; Davies AR; Srivastava M; Sheridan JM; Sng XYX; Delmonte OM; Dobbs K; Loh KL; Miosge LA; Lee CE; Chand R; Chan A; Yap JY; Keller MD; Chen K; Rossjohn J; la Gruta NL; Vinuesa CG; Reid HH; Lionakis MS; Notarangelo LD; Gray DHD; Goodnow CC; Cook MC; Daley SR, 2021, 'Nfkb2 variants reveal a p100-degradation threshold that defines autoimmune susceptibility', Journal of Experimental Medicine, 218, http://dx.doi.org/10.1084/JEM.20200476
2021
Russell AJ; Gray PE; Ziegler JB; Kim YJ; Smith S; Sewell WA; Goodnow CC, 2021, 'SAMD9L autoinflammatory or ataxia pancytopenia disease mutations activate cell-autonomous translational repression', Proceedings of the National Academy of Sciences of the United States of America, 118, http://dx.doi.org/10.1073/pnas.2110190118
2021
Masle-Farquhar E; Russell A; Li Y; Zhu F; Rui L; Brink R; Goodnow CC, 2021, 'Loss-of-function of Fbxo10, encoding a post-translational regulator of BCL2 in lymphomas, has no discernible effect on BCL2 or B lymphocyte accumulation in mice', PLoS ONE, 16, pp. e0237830, http://dx.doi.org/10.1371/journal.pone.0237830
2021
Wagle MV; Vervoort SJ; Kelly MJ; Van Der Byl W; Peters TJ; Martin BP; Martelotto LG; Nüssing S; Ramsbottom KM; Torpy JR; Knight D; Reading S; Thia K; Miosge LA; Howard DR; Gloury R; Gabriel SS; Utzschneider DT; Oliaro J; Powell JD; Luciani F; Trapani JA; Johnstone RW; Kallies A; Goodnow CC; Parish IA, 2021, 'Antigen-driven EGR2 expression is required for exhausted CD8+ T cell stability and maintenance', Nature Communications, 12, pp. 2782, http://dx.doi.org/10.1038/s41467-021-23044-9
2021
Kayagaki N; Kornfeld OS; Lee BL; Stowe IB; O’Rourke K; Li Q; Sandoval W; Yan D; Kang J; Xu M; Zhang J; Lee WP; McKenzie BS; Ulas G; Payandeh J; Roose-Girma M; Modrusan Z; Reja R; Sagolla M; Webster JD; Cho V; Andrews TD; Morris LX; Miosge LA; Goodnow CC; Bertram EM; Dixit VM, 2021, 'NINJ1 mediates plasma membrane rupture during lytic cell death', Nature, 591, pp. 131 - 136, http://dx.doi.org/10.1038/s41586-021-03218-7
2021
Peters TJ; Buckley MJ; Chen Y; Smyth GK; Goodnow CC; Clark SJ, 2021, 'Calling differentially methylated regions from whole genome bisulphite sequencing with DMRcate', Nucleic Acids Research, 49, pp. e109, http://dx.doi.org/10.1093/nar/gkab637
2021
Randall KL; Law HD; Ziolkowski AF; Wirasinha RC; Goodnow CC; Daley SR, 2021, 'DOCK8 deficiency diminishes thymic T-regulatory cell development but not thymic deletion', Clinical and Translational Immunology, 10, pp. e1236, http://dx.doi.org/10.1002/cti2.1236
2021
Boast B; Miosge LA; Kuehn HS; Cho V; Athanasopoulos V; McNamara HA; Sontani Y; Mei Y; Howard D; Sutton HJ; Omari SA; Yu Z; Nasreen M; Daniel Andrews T; Cockburn IA; Goodnow CC; Rosenzweig SD; Enders A, 2021, 'A point mutation in IKAROS ZF1 causes a B cell deficiency in mice', Journal of Immunology, 206, pp. 1505 - 1514, http://dx.doi.org/10.4049/jimmunol.1901464
2021
Yabas M; Yazicioglu YF; Hoyne GF; Goodnow CC; Enders A, 2021, 'Loss of hnRNPLL-dependent splicing of Ptprc has no impact on B-cell development, activation and terminal differentiation into antibody-secreting cells', Immunology and Cell Biology, 99, pp. 532 - 541, http://dx.doi.org/10.1111/imcb.12433
2021
Goodnow CC, 2021, 'COVID-19, varying genetic resistance to viral disease and immune tolerance checkpoints', Immunology and Cell Biology, 99, pp. 177 - 191, http://dx.doi.org/10.1111/imcb.12419
2021
Burnett DL; Jackson KJL; Langley DB; Aggrawal A; Stella AO; Johansen MD; Balachandran H; Lenthall H; Rouet R; Walker G; Saunders BM; Singh M; Li H; Henry JY; Jackson J; Stewart AG; Witthauer F; Spence MA; Hansbro NG; Jackson C; Schofield P; Milthorpe C; Martinello M; Schulz SR; Roth E; Kelleher A; Emery S; Britton WJ; Rawlinson WD; Karl R; Schäfer S; Winkler TH; Brink R; Bull RA; Hansbro PM; Jäck HM; Turville S; Christ D; Goodnow CC, 2021, 'Immunizations with diverse sarbecovirus receptor-binding domains elicit SARS-CoV-2 neutralizing antibodies against a conserved site of vulnerability', Immunity, 54, pp. 2908 - 2921.e6, http://dx.doi.org/10.1016/j.immuni.2021.10.019
2021
Zhang Z; Jara CJ; Singh M; Xu H; Goodnow CC; Jackson KJL; Reed JH, 2021, 'Human transitional and IgMlow mature naïve B cells preserve permissive B-cell receptors', Immunology and Cell Biology, 99, pp. 865 - 878, http://dx.doi.org/10.1111/imcb.12478
2021
Burnett DL; Schofield P; Langley DB; Jackson J; Bourne K; Wilson E; Porebski BT; Buckle AM; Brink R; Goodnow CC; Christ D, 2020, 'Conformational diversity facilitates antibody mutation trajectories and discrimination between foreign and self-antigens', Proceedings of the National Academy of Sciences of the United States of America, 117, pp. 22341 - 22350, http://dx.doi.org/10.1073/pnas.2005102117
2020
Masle-Farquhar E; Payne K; Singh M; Rao G; Al-Eryani G; Jara C; Jackson K; Brink RA; Tangye S; Reed J; Goodnow CC, 2020, 'The effects of germline STAT3-activating mutations from autoimmunity and lymphoid malignancy on mouse and human T cells', The Journal of Immunology, 204, pp. 142.35 - 142.35, http://dx.doi.org/10.4049/jimmunol.204.supp.142.35
2020
Stirzaker C; Skvortsova K; Masle-Farquhar E; Goodnow C; Clark SJ, 2020, 'Epigenetic changes during tumour development – Functional epigenetics study', Pathology, vol. 52, pp. S29 - S29, http://dx.doi.org/10.1016/j.pathol.2020.01.121
2020
Lau A; Avery DT; Jackson K; Lenthall H; Volpi S; Brigden H; Russell AJ; Bier J; Reed JH; Smart JM; Cole T; Choo S; Gray PE; Berglund LJ; Hsu P; Wong M; O'Sullivan M; Boztug K; Meyts I; Uzel G; Notarangelo LD; Brink R; Goodnow CC; Tangye SG; Deenick EK, 2020, 'Activated PI3Kd breaches multiple B cell tolerance checkpoints and causes autoantibody production', Journal of Experimental Medicine, 217, http://dx.doi.org/10.1084/jem_20191336
2020
Singh M; Jackson KJL; Wang JJ; Schofield P; Field MA; Koppstein D; Peters TJ; Burnett DL; Rizzetto S; Nevoltris D; Masle-Farquhar E; Faulks ML; Russell A; Gokal D; Hanioka A; Horikawa K; Colella AD; Chataway TK; Blackburn J; Mercer TR; Langley DB; Goodall DM; Jefferis R; Gangadharan Komala M; Kelleher AD; Suan D; Rischmueller M; Christ D; Brink R; Luciani F; Gordon TP; Goodnow CC; Reed JH, 2020, 'Lymphoma Driver Mutations in the Pathogenic Evolution of an Iconic Human Autoantibody', Cell, 180, pp. 878 - 894.e19, http://dx.doi.org/10.1016/j.cell.2020.01.029
2020
Rouet R; Mazigi O; Walker G; Langley D; Sobti M; Schofield P; Lenthall H; Jackson J; Ubiparipovic S; Henry J; Abayasingam A; Burnett D; Kelleher A; Brink R; Bull R; Turville S; Stewart A; Goodnow C; Rawlinson W; Christ D, 2020, 'Potent SARS-CoV-2 binding and neutralization through maturation of iconic SARS-CoV-1 antibodies', , http://dx.doi.org/10.1101/2020.12.14.422791
2020
Koay HF; Su S; Amann-Zalcenstein D; Daley SR; Comerford I; Whyte CE; Konstantinov IE; d’Udekem Y; Baldwin T; Hickey PF; Berzins SP; Mak JYW; Kallies A; Chen Z; Nussing S; Kedzierska K; Mackay LK; McColl SR; Deenick EK; Fairlie DP; McCluskey J; Goodnow CC; Ritchie ME; Belz GT; Naik SH; Pellicci DG; Godfrey DI, 2020, 'A divergent transcriptional landscape underpins the development and functional branching of MAIT cells', The Journal of Immunology, 204, pp. 223.8 - 223.8, http://dx.doi.org/10.4049/jimmunol.204.supp.223.8
2020
Zammit N; Siggs OM; Gray P; King C; Christ D; Goodnow CC; Grey S, 2019, 'Phospho-tuning immunity through Denisovan, modern human and mouse TNFAIP3 gene variants', bioRxiv, http://dx.doi.org/10.1101/589507
2019
Jeelall Y; Singh M; Lai J; Ali S; Jackson K; Hollingsworth P; De Boer B; Wood B; Reed J; Goodnow C; Mclean-Tooke A; Lucas M, 2019, 'Oligoclonal lymphocytosis and cytokine derangement in a case of severe adverse drug reaction', Pathology, 51, pp. S131 - S131, http://dx.doi.org/10.1016/j.pathol.2018.12.378
2019
Singh M; Al-Eryani G; Carswell S; Ferguson JM; Blackburn J; Barton K; Roden D; Luciani F; Giang Phan T; Junankar S; Jackson K; Goodnow CC; Smith MA; Swarbrick A, 2019, 'High-throughput targeted long-read single cell sequencing reveals the clonal and transcriptional landscape of lymphocytes', Nature Communications, 10, pp. 3120, http://dx.doi.org/10.1038/s41467-019-11049-4
2019
Koay HF; Su S; Amann-Zalcenstein D; Daley SR; Comerford I; Miosge L; Whyte CE; Konstantinov IE; D'Udekem Y; Baldwin T; Hickey PF; Berzins SP; Mak JYW; Sontani Y; Roots CM; Sidwell T; Kallies A; Chen Z; Nüssing S; Kedzierska K; Mackay LK; McColl SR; Deenick EK; Fairlie DP; McCluskey J; Goodnow CC; Ritchie ME; Belz GT; Naik SH; Pellicci DG; Godfrey DI, 2019, 'A divergent transcriptional landscape underpins the development and functional branching of MAIT cells', Science Immunology, 4, http://dx.doi.org/10.1126/sciimmunol.aay6039
2019
Barnet M; Pathmanandavel S; McCarthy L; Goodnow C; Joshua A, 2019, 'The Australian Exceptional Responders Program: A national collaboration', Annals of Oncology, vol. 30, pp. v794 - v795, http://dx.doi.org/10.1093/annonc/mdz268.104
2019
Skvortsova K; Masle-Farquhar E; Luu PL; Song JZ; Qu W; Zotenko E; Gould CM; Du Q; Peters TJ; Colino-Sanguino Y; Pidsley R; Nair SS; Khoury A; Smith GC; Miosge LA; Reed JH; Kench JG; Rubin MA; Horvath L; Bogdanovic O; Lim SM; Polo JM; Goodnow CC; Stirzaker C; Clark SJ, 2019, 'DNA Hypermethylation Encroachment at CpG Island Borders in Cancer Is Predisposed by H3K4 Monomethylation Patterns', Cancer Cell, 35, pp. 297 - 314.e8, http://dx.doi.org/10.1016/j.ccell.2019.01.004
2019
Burnett DL; Reed JH; Christ D; Goodnow CC, 2019, 'Clonal redemption and clonal anergy as mechanisms to balance B cell tolerance and immunity', Immunological Reviews, 292, pp. 61 - 75, http://dx.doi.org/10.1111/imr.12808
2019
Kayagaki N; Lee BL; Stowe IB; Kornfeld OS; O'Rourke K; Mirrashidi KM; Haley B; Watanabe C; Roose-Girma M; Modrusan Z; Kummerfeld S; Reja R; Zhang Y; Cho V; Daniel Andrews T; Morris LX; Goodnow CC; Bertram EM; Dixit VM, 2019, 'IRF2 transcriptionally induces GSDMD expression for pyroptosis', Science Signaling, 12, http://dx.doi.org/10.1126/scisignal.aax4917
2019
Policheni A; Horikawa K; Milla L; Kofler J; Bouillet P; Belz GT; O'Reilly LA; Goodnow CC; Strasser A; Gray DHD, 2019, 'CARD11 is dispensable for homeostatic responses and suppressive activity of peripherally induced FOXP3+ regulatory T cells', Immunology and Cell Biology, 97, pp. 740 - 752, http://dx.doi.org/10.1111/imcb.12268
2019
Wirasinha RC; Chan A; Yap JY; Hu DY; Teh CE; Gray DHD; Goodnow CC; Daley SR, 2019, 'Deletion of self-reactive CCR7– thymocytes in the absence of MHC expression on thymic epithelial cells', Cell Death and Differentiation, 26, pp. 2727 - 2739, http://dx.doi.org/10.1038/s41418-019-0331-8
2019
Moran I; Avery DT; Payne K; Lenthall H; Davies EG; Burns S; Ip W; Oleastro MM; Reisli I; Guner S; Keles S; Notarangelo L; Deenick EK; Goodnow CC; Zahra D; Brink R; Wong M; Tangye SG; Ma CS; Phan TG, 2019, 'B cell–intrinsic requirement for STK4 in humoral immunity in mice and human subjects', Journal of Allergy and Clinical Immunology, 143, pp. 2302 - 2305, http://dx.doi.org/10.1016/j.jaci.2019.02.010
2019
Zammit NW; Siggs OM; Gray PE; Horikawa K; Langley DB; Walters SN; Daley SR; Loetsch C; Warren J; Yap JY; Cultrone D; Russell A; Malle EK; Villanueva JE; Cowley MJ; Gayevskiy V; Dinger ME; Brink R; Zahra D; Chaudhri G; Karupiah G; Whittle B; Roots C; Bertram E; Yamada M; Jeelall Y; Enders A; Clifton BE; Mabbitt PD; Jackson CJ; Watson SR; Jenne CN; Lanier LL; Wiltshire T; Spitzer MH; Nolan GP; Schmitz F; Aderem A; Porebski BT; Buckle AM; Abbott DW; Ziegler JB; Craig ME; Benitez-Aguirre P; Teo J; Tangye SG; King C; Wong M; Cox MP; Phung W; Tang J; Sandoval W; Wertz IE; Christ D; Goodnow CC; Grey ST, 2019, 'Denisovan, modern human and mouse TNFAIP3 alleles tune A20 phosphorylation and immunity', Nature Immunology, 20, pp. 1299 - 1310, http://dx.doi.org/10.1038/s41590-019-0492-0
2019
Siggs OM; Russell A; Singh-Grewal D; Wong M; Chan P; Craig ME; O'Loughlin T; Stormon M; Goodnow CC, 2019, 'Preponderance of CTLA4 Variation Associated With Autosomal Dominant Immune Dysregulation in the MYPPPY Motif', Frontiers in Immunology, 10, pp. 1544, http://dx.doi.org/10.3389/fimmu.2019.01544
2019
Yap JY; Wirasinha RC; Chan A; Howard DR; Goodnow CC; Daley SR, 2018, 'Indirect presentation in the thymus limits naive and regulatory T-cell differentiation by promoting deletion of self-reactive thymocytes', Immunology, 154, pp. 522 - 532, http://dx.doi.org/10.1111/imm.12904
2018
Wang JJ; Reed JH; Colella AD; Russell AJ; Murray-Brown W; Chataway TK; Jackson KJL; Goodnow CC; Gordon TP, 2018, 'Molecular Profiling and Clonal Tracking of Secreted Rheumatoid Factors in Primary Sjögren's Syndrome', Arthritis and Rheumatology, 70, pp. 1617 - 1625, http://dx.doi.org/10.1002/art.40539
2018
Wirasinha RC; Singh M; Archer SK; Chan A; Harrison PF; Goodnow CC; Daley SR, 2018, 'αβ T-cell receptors with a central CDR3 cysteine are enriched in CD8αα intraepithelial lymphocytes and their thymic precursors', Immunology and Cell Biology, 96, pp. 553 - 561, http://dx.doi.org/10.1111/imcb.12047
2018
Rizzetto S; Koppstein DNP; Samir J; Singh M; Reed JH; Cai CH; Lloyd AR; Eltahla AA; Goodnow CC; Luciani F, 2018, 'B-cell receptor reconstruction from single-cell RNA-seq with VDJPuzzle', Bioinformatics, 34, pp. 2846 - 2847, http://dx.doi.org/10.1093/BIOINFORMATICS/BTY171
2018
Alshekaili J; Chand R; Lee CE; Corley S; Kwong K; Papa I; Fulcher DA; Randall KL; Leiding JW; Ma CS; Wilkins MR; Uzel G; Goodnow CC; Vinuesa CG; Tangye SG; Cook MC, 2018, 'STAT3 regulates cytotoxicity of human CD57+ CD4+ T cells in blood and lymphoid follicles', Scientific Reports, 8, http://dx.doi.org/10.1038/s41598-018-21389-8
2018
Barnet MB; Blinman P; Cooper W; Boyer MJ; Kao S; Goodnow CC, 2018, 'Understanding Immune Tolerance of Cancer: Re-Purposing Insights from Fetal Allografts and Microbes', BioEssays, 40, http://dx.doi.org/10.1002/bies.201800050
2018
Burnett DL; Langley DB; Schofield P; Hermes JR; Chan TD; Jackson J; Bourne K; Reed JH; Patterson K; Porebski BT; Brink R; Christ D; Goodnow CC, 2018, 'Germinal center antibody mutation trajectories are determined by rapid self/foreign discrimination', Science, 360, pp. 223 - 226, http://dx.doi.org/10.1126/science.aao3859
2018
Singh M; Al-Eryani G; Carswell S; Ferguson J; Blackburn J; Barton K; Roden D; Luciani F; Phan T; Junankar S; Jackson K; Goodnow C; Smith M; Swarbrick A, 2018, 'High-throughput targeted long-read single cell sequencing reveals the clonal and transcriptional landscape of lymphocytes', High-throughput targeted long-read single cell sequencing reveals the clonal and transcriptional landscape of lymphocytes, http://dx.doi.org/10.1101/424945
2018
Wagle MV; Marchingo JM; Howitt J; Tan SS; Goodnow CC; Parish IA, 2018, 'The Ubiquitin Ligase Adaptor NDFIP1 Selectively Enforces a CD8+ T Cell Tolerance Checkpoint to High-Dose Antigen', Cell Reports, 24, pp. 577 - 584, http://dx.doi.org/10.1016/j.celrep.2018.06.060
2018
Petersons CJ; Mangelsdorf BL; Poljak A; Smith MD; Greenfield JR; Thompson CH; Burt MG, 2017, 'Low dose prednisolone and insulin sensitivity differentially affect arterial stiffness and endothelial function: An open interventional and cross-sectional study', Atherosclerosis, 258, pp. 34 - 39, http://dx.doi.org/10.1016/j.atherosclerosis.2017.01.033
2017
Oakes SR; Gallego-Ortega D; Stanford PM; Junankar S; Au WWY; Kikhtyak Z; von Korff A; Sergio CM; Law AMK; Castillo LE; Allerdice SL; Young AIJ; Piggin C; Whittle B; Bertram E; Naylor MJ; Roden DL; Donovan J; Korennykh A; Goodnow CC; O’Bryan MK; Ormandy CJ, 2017, 'A mutation in the viral sensor 2’-5’-oligoadenylate synthetase 2 causes failure of lactation', PLoS Genetics, 13, http://dx.doi.org/10.1371/journal.pgen.1007072
2017
Wang JQ; Jeelall YS; Humburg P; Batchelor EL; Kaya SM; Yoo HM; Goodnow CC; Horikawa K, 2017, 'Synergistic cooperation and crosstalk between MYD88L265P and mutations that dysregulate CD79B and surface IgM', Journal of Experimental Medicine, 214, pp. 2759 - 2776, http://dx.doi.org/10.1084/jem.20161454
2017
Hu DY; Wirasinha RC; Goodnow CC; Daley SR, 2017, 'IL-2 prevents deletion of developing T-regulatory cells in the thymus', Cell Death and Differentiation, 24, pp. 1007 - 1016, http://dx.doi.org/10.1038/cdd.2017.38
2017
Langley DB; Crossett B; Schofield P; Jackson J; Zeraati M; Maltby D; Christie M; Burnett D; Brink R; Goodnow C; Christ D, 2017, 'Structural basis of antigen recognition: Crystal structure of duck egg lysozyme', Acta Crystallographica Section D: Structural Biology, 73, pp. 910 - 920, http://dx.doi.org/10.1107/S2059798317013730
2017
Burnett DL; Parish IA; Masle-Farquhar E; Brink R; Goodnow CC, 2017, 'Murine LRBA deficiency causes CTLA-4 deficiency in Tregs without progression to immune dysregulation', Immunology and Cell Biology, 95, pp. 775 - 788, http://dx.doi.org/10.1038/icb.2017.50
2017
McNamara HA; Cai Y; Wagle MV; Sontani Y; Roots CM; Miosge LA; O’Connor JH; Sutton HJ; Ganusov VV; Heath WR; Bertolino P; Goodnow CG; Parish IA; Enders A; Cockburn IA, 2017, 'Up-regulation of LFA-1 allows liver-resident memory T cells to patrol and remain in the hepatic sinusoids', Science Immunology, 2, http://dx.doi.org/10.1126/sciimmunol.aaj1996
2017
Isaacs M; Tonks KT; Greenfield JR, 2017, 'Euglycaemic diabetic ketoacidosis in patients using sodium-glucose co-transporter 2 inhibitors', Internal Medicine Journal, 47, pp. 701 - 704, http://dx.doi.org/10.1111/imj.13442
2017
Tangye SG; Pillay B; Randall KL; Avery DT; Phan TG; Gray P; Ziegler JB; Smart JM; Peake J; Arkwright PD; Hambleton S; Orange J; Goodnow CC; Uzel G; Casanova JL; Lugo Reyes SO; Freeman AF; Su HC; Ma CS, 2017, 'Dedicator of cytokinesis 8–deficient CD4+ T cells are biased to a TH2 effector fate at the expense of TH1 and TH17 cells', Journal of Allergy and Clinical Immunology, 139, pp. 933 - 949, http://dx.doi.org/10.1016/j.jaci.2016.07.016
2017
Chen DLT; Brown R; Liess C; Poljak A; Xu A; Zhang J; Trenell M; Jenkins A; Chisholm D; Samocha-Bonet D; Macefield VG; Greenfield JR, 2017, 'Muscle sympathetic nerve activity is associated with liver insulin sensitivity in obese non-diabetic men', Frontiers in Physiology, 8, http://dx.doi.org/10.3389/fphys.2017.00101
2017
Rizzetto S; Koppstein DNP; Samir J; Singh M; Reed J; Cai C; Lloyd A; Eltahla A; Goodnow C; Luciani F, 2017, 'B-cell receptor reconstruction from single-cell RNA-seq with VDJPuzzle', , http://dx.doi.org/10.1101/181156
2017
Miosge LA; Sontani Y; Chuah A; Horikawa K; Russell TA; Meia Y; Wagle MV; Howard DR; Enders A; Tscharke DC; Goodnow CC; Parish IA, 2017, 'Systems-guided forward genetic screen reveals a critical role of the replication stress response protein ETAA1 in T cell clonal expansion', Proceedings of the National Academy of Sciences of the United States of America, 114, pp. E5216 - E5225, http://dx.doi.org/10.1073/pnas.1705795114
2017
Tangye SG; Pillay B; Randall KL; Avery DT; Tri GP; Gray P; Ziegler JB; Smart JM; Peake J; Arkwright PD; Hambleton S; Orange J; Goodnow CC; Uzel G; Casanova J-L; Lugo Reyes SO; Freeman AF; Su HC; Ma CS, 2017, 'Dedicator of cytokinesis 8-deficient CD4(+) T cells are biased to a T(H)2 effector fate at the expense of T(H)1 and T(H)17 cells', JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, vol. 139, pp. 933 - 949, http://dx.doi.org/10.1016/j.jaci.2016.07.016
2017
Hu DY; Yap JY; Wirasinha RC; Howard DR; Goodnow CC; Daley SR, 2016, 'A timeline demarcating two waves of clonal deletion and Foxp3 upregulation during thymocyte development', Immunology and Cell Biology, 94, pp. 357 - 366, http://dx.doi.org/10.1038/icb.2015.95
2016
Wang JQ; Beutler B; Goodnow CC; Horikawa K, 2016, 'Inhibiting TLR9 and other UNC93B1-dependent TLRs paradoxically increases accumulation of MYD88L265P plasmablasts in vivo', Blood, 128, pp. 1604 - 1608, http://dx.doi.org/10.1182/blood-2016-03-708065
2016
Sabouri Z; Perotti S; Spierings E; Humburg P; Yabas M; Bergmann H; Horikawa K; Roots C; Lambe S; Young C; Andrews TD; Field M; Enders A; Reed JH; Goodnow CC, 2016, 'IgD attenuates the IgM-induced anergy response in transitional and mature B cells', Nature Communications, 7, http://dx.doi.org/10.1038/ncomms13381
2016
Reed JH; Jackson J; Christ D; Goodnow CC, 2016, 'Clonal redemption of autoantibodies by somatic hypermutation away from self-reactivity during human immunization', Journal of Experimental Medicine, 213, pp. 1255 - 1265, http://dx.doi.org/10.1084/jem.20151978
2016
Dooley J; Tian L; Schonefeldt S; Delghingaro-Augusto V; Garcia-Perez JE; Pasciuto E; Di Marino D; Carr EJ; Oskolkov N; Lyssenko V; Franckaert D; Lagou V; Overbergh L; Vandenbussche J; Allemeersch J; Chabot-Roy G; Dahlstrom JE; Laybutt DR; Petrovsky N; Socha L; Gevaert K; Jetten AM; Lambrechts D; Linterman MA; Goodnow CC; Nolan CJ; Lesage S; Schlenner SM; Liston A, 2016, 'Genetic predisposition for beta cell fragility underlies type 1 and type 2 diabetes', Nature Genetics, 48, pp. 519 - 527, http://dx.doi.org/10.1038/ng.3531
2016
Smith FC; Kumar SS; Furlong TJ; Gangaram SV; Greenfield JR; Stocker SL; Graham GG; Williams KM; Day RO, 2016, 'Pharmacokinetics of Metformin in Patients Receiving Regular Hemodiafiltration', American Journal of Kidney Diseases, 68, pp. 990 - 992, http://dx.doi.org/10.1053/j.ajkd.2016.08.017
2016
Wu Z; Liang R; Ohnesorg T; Cho V; Lam W; Abhayaratna WP; Gatenby PA; Perera C; Zhang Y; Whittle B; Sinclair A; Goodnow CC; Field M; Andrews TD; Cook MC, 2016, 'Heterogeneity of Human Neutrophil CD177 Expression Results from CD177P1 Pseudogene Conversion', PLoS Genetics, 12, http://dx.doi.org/10.1371/journal.pgen.1006067
2016
Koay HF; Gherardin NA; Enders A; Loh L; Mackay LK; Almeida CF; Russ BE; Nold-Petry CA; Nold MF; Bedoui S; Chen Z; Corbett AJ; Eckle SBG; Meehan B; D'Udekem Y; Konstantinov IE; Lappas M; Liu L; Goodnow CC; Fairlie DP; Rossjohn J; Chong MM; Kedzierska K; Berzins SP; Belz GT; McCluskey J; Uldrich AP; Godfrey DI; Pellicci DG, 2016, 'A three-stage intrathymic development pathway for the mucosal-associated invariant T cell lineage', Nature Immunology, 17, pp. 1300 - 1311, http://dx.doi.org/10.1038/ni.3565
2016
Cho JH; Kim HO; Ju YJ; Kye YC; Lee GW; Lee SW; Yun CH; Bottini N; Webster K; Goodnow CC; Surh CD; King C; Sprent J, 2016, 'CD45-mediated control of TCR tuning in naïve and memory CD8+ T cells', Nature Communications, 7, http://dx.doi.org/10.1038/ncomms13373
2016
Lee P; Bova R; Schofield L; Bryant W; Dieckmann W; Slattery A; Govendir MA; Emmett L; Greenfield JR, 2016, 'Brown Adipose Tissue Exhibits a Glucose-Responsive Thermogenic Biorhythm in Humans', Cell Metabolism, 23, pp. 602 - 609, http://dx.doi.org/10.1016/j.cmet.2016.02.007
2016
De Sousa SMC; Haghighi KS; Qiu MR; Greenfield JR; Chen DLT, 2016, 'Synchronous Nesidioblastosis, Endocrine Microadenoma, and Intraductal Papillary Mucinous Neoplasia in a Man Presenting with Hyperinsulinemic Hypoglycemia', Pancreas, 45, pp. 154 - 159, http://dx.doi.org/10.1097/MPA.0000000000000430
2016
Moon J; Kumar SS; Graham GG; Baysari MT; Williams KM; Chen W; Viardot A; Greenfield JR; Day RO, 2016, 'Trends in metformin utilisation and dose appropriateness in Australia', European Journal of Clinical Pharmacology, 72, pp. 1489 - 1496, http://dx.doi.org/10.1007/s00228-016-2117-y
2016
Hillhouse EE; Liston A; Collin R; Desautels E; Goodnow CC; Lesage S, 2016, 'TCR transgenic mice reveal the impact of type 1 diabetes loci on early and late disease checkpoints', Immunology and Cell Biology, 94, pp. 709 - 713, http://dx.doi.org/10.1038/icb.2016.27
2016
Wertz IE; Newton K; Seshasayee D; Kusam S; Lam C; Zhang J; Popovych N; Helgason E; Schoeffler A; Jeet S; Ramamoorthi N; Kategaya L; Newman RJ; Horikawa K; Dugger D; Sandoval W; Mukund S; Zindal A; Martin F; Quan C; Tom J; Fairbrother WJ; Townsend M; Warming S; DeVoss J; Liu J; Dueber E; Caplazi P; Lee WP; Goodnow CC; Balazs M; Yu K; Kolumam G; Dixit VM, 2016, 'Erratum: Phosphorylation and linear ubiquitin direct A20 inhibition of inflammation (Nature (2015) 528 (370-375) (DOI:10.1038/nature16165))', Nature, 532, pp. 402, http://dx.doi.org/10.1038/nature16541
2016
Ellyard JI; Jerjen R; Martin JL; Lee A; Field MA; Jiang SH; Cappello J; Naumann SK; Andrews TD; Scott HS; Casarotto MG; Goodnow CC; Chaitow J; Pascual V; Hertzog P; Alexander SI; Cook MC; Vinuesa CG, 2016, 'Identification of a pathogenic variant in TREX1 in early-onset cerebral SLE by whole-exome sequencing', Pathology, vol. 48, pp. S47 - S47, http://dx.doi.org/10.1016/j.pathol.2015.12.120
2016
Lam T; Hoffman DM; Cukier K; Darnell D; Greenfield JR; Harrison N; Hng TM; Morrow AF; Cheung NW, 2016, 'Temporal HbA1c patterns amongst patients with type 2 diabetes referred for specialist care: Data from the S4S-DINGO-Diabetes Informatics Group', Diabetes Research and Clinical Practice, 116, pp. 159 - 164, http://dx.doi.org/10.1016/j.diabres.2016.04.006
2016
He J; Chen DL; Samocha-Bonet D; Gillinder KR; Barclay JL; Magor GW; Perkins AC; Greenfield JR; Yang G; Whitehead JP, 2016, 'Fibroblast growth factor-1 (FGF-1) promotes adipogenesis by downregulation of carboxypeptidase A4 (CPA4)–a negative regulator of adipogenesis implicated in the modulation of local and systemic insulin sensitivity', Growth Factors, 34, pp. 210 - 216, http://dx.doi.org/10.1080/08977194.2017.1285764
2016
Lee-Young RS; Hoffman NJ; Murphy KT; Henstridge DC; Samocha-Bonet D; Siebel AL; Iliades P; Zivanovic B; Hong YH; Colgan TD; Kraakman MJ; Bruce CR; Gregorevic P; McConell GK; Lynch GS; Drummond GR; Kingwell BA; Greenfield JR; Febbraio MA, 2016, 'Glucose-6-phosphate dehydrogenase contributes to the regulation of glucose uptake in skeletal muscle', Molecular Metabolism, 5, pp. 1083 - 1091, http://dx.doi.org/10.1016/j.molmet.2016.09.002
2016
Janssen E; Tohme M; Hedayat M; Leick M; Kumari S; Ramesh N; Massaad MJ; Ullas S; Azcutia V; Goodnow CC; Randall KL; Qiao Q; Wu H; Al-Herz W; Cox D; Hartwig J; Irvine DJ; Luscinskas FW; Geha RS, 2016, 'A DOCK8-WIP-WASp complex links T cell receptors to the actin cytoskeleton', Journal of Clinical Investigation, 126, pp. 3837 - 3851, http://dx.doi.org/10.1172/JCI85774
2016
Andrews TD; Jeelall Y; Talaulikar D; Goodnow CC; Field MA, 2016, 'DeepSNVMiner: A sequence analysis tool to detect emergent, rare mutations in subsets of cell populations', PeerJ, 2016, http://dx.doi.org/10.7717/peerj.2074
2016
Parish IA; Stamp LA; Lorenzo AMD; Fowler SM; Sontani Y; Miosge LA; Howard DR; Goodnow CC; Young HM; Furness JB, 2016, 'A Novel Mutation in Nucleoporin 35 Causes Murine Degenerative Colonic Smooth Muscle Myopathy', American Journal of Pathology, 186, pp. 2254 - 2261, http://dx.doi.org/10.1016/j.ajpath.2016.04.016
2016
Tonks KT; Coster AC; Christopher MJ; Chaudhuri R; Xu A; Gagnon-Bartsch J; Chisholm DJ; James DE; Meikle PJ; Greenfield JR; Samocha-Bonet D, 2016, 'Skeletal muscle and plasma lipidomic signatures of insulin resistance and overweight/obesity in humans', Obesity, 24, pp. 908 - 916, http://dx.doi.org/10.1002/oby.21448
2016
Bishay RH; Greenfield JR, 2016, 'A review of maturity onset diabetes of the young (MODY) and challenges in the management of glucokinase-MODY', Medical Journal of Australia, 205, pp. 480 - 485, http://dx.doi.org/10.5694/MJA16.00458
2016
Greenfield JRF; Kuhn S; Mehler D; Puel F; Rommens PM, 2015, 'Biomechanical evaluation of a new treatment method for distal tibia fractures', COMPUTER METHODS IN BIOMECHANICS AND BIOMEDICAL ENGINEERING, 18, pp. 1952 - 1953, http://dx.doi.org/10.1080/10255842.2015.1069582
2015
Miosge LA; Field MA; Sontani Y; Cho V; Johnson S; Palkova A; Balakishnan B; Liang R; Zhang Y; Lyon S; Beutler B; Whittle B; Bertram EM; Enders A; Goodnow CC; Andrewsa TD, 2015, 'Comparison of predicted and actual consequences of missense mutations', Proceedings of the National Academy of Sciences of the United States of America, 112, pp. E5189 - E5198, http://dx.doi.org/10.1073/pnas.1511585112
2015
Kayagaki N; Stowe IB; Lee BL; O'Rourke K; Anderson K; Warming S; Cuellar T; Haley B; Roose-Girma M; Phung QT; Liu PS; Lill JR; Li H; Wu J; Kummerfeld S; Zhang J; Lee WP; Snipas SJ; Salvesen GS; Morris LX; Fitzgerald L; Zhang Y; Bertram EM; Goodnow CC; Dixit VM, 2015, 'Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling', Nature, 526, pp. 666 - 671, http://dx.doi.org/10.1038/nature15541
2015
Sapkota S; Brien J-AE; Greenfield JR; Aslani P, 2015, 'A Systematic Review of Interventions Addressing Adherence to Anti-Diabetic Medications in Patients with Type 2 Diabetes—Components of Interventions', PLOS ONE, vol. 10, pp. e0128581 - e0128581, http://dx.doi.org/10.1371/journal.pone.0128581
2015
Siggs OM; Miosge LA; Daley SR; Asquith K; Foster PS; Liston A; Goodnow CC, 2015, 'Quantitative reduction of the TCR adapter protein SLP-76 unbalances immunity and immune regulation', Journal of Immunology, 194, pp. 2587 - 2595, http://dx.doi.org/10.4049/jimmunol.1400326
2015
Flesch IEA; Randall KL; Hollett NA; Di Law H; Miosge LA; Sontani Y; Goodnow CC; Tscharke DC, 2015, 'Delayed control of herpes simplex virus infection and impaired CD4+ T-cell migration to the skin in mouse models of DOCK8 deficiency', Immunology and Cell Biology, 93, pp. 517 - 521, http://dx.doi.org/10.1038/icb.2015.32
2015
Lee P; Greenfield JR, 2015, 'Non-pharmacological and pharmacological strategies of brown adipose tissue recruitment in humans', Molecular and Cellular Endocrinology, 418, pp. 184 - 190, http://dx.doi.org/10.1016/j.mce.2015.05.025
2015
Wertz IE; Newton K; Seshasayee D; Kusam S; Lam C; Zhang J; Popovych N; Helgason E; Schoeffler A; Jeet S; Ramamoorthi N; Kategaya L; Newman RJ; Horikawa K; Dugger D; Sandoval W; Mukund S; Zindal A; Martin F; Quan C; Tom J; Fairbrother WJ; Townsend M; Warming S; Devoss J; Liu J; Dueber E; Caplazi P; Lee WP; Goodnow CC; Balazs M; Yu K; Kolumam G; Dixit VM, 2015, 'Phosphorylation and linear ubiquitin direct A20 inhibition of inflammation', Nature, 528, pp. 370 - 375, http://dx.doi.org/10.1038/nature16165
2015
Chen DL; Liess C; Poljak A; Xu A; Zhang J; Thoma C; Trenell M; Milner B; Jenkins AB; Chisholm DJ; Samocha-Bonet D; Greenfield JR, 2015, 'Phenotypic characterization of insulin-resistant and insulin-sensitive obesity', Journal of Clinical Endocrinology and Metabolism, 100, pp. 4082 - 4091, http://dx.doi.org/10.1210/jc.2015-2712
2015
Lim SL; Qu ZP; Kortschak RD; Lawrence DM; Geoghegan J; Hempfling A-L; Bergmann M; Goodnow CC; Ormandy CJ; Wong L; Mann J; Scott HS; Jamsai D; Adelson DL; O'Bryan MK, 2015, 'Correction: HENMT1 and piRNA Stability Are Required for Adult Male Germ Cell Transposon Repression and to Define the Spermatogenic Program in the Mouse.', PLoS Genet, 11, pp. e1005782, http://dx.doi.org/10.1371/journal.pgen.1005782
2015
Johar AS; Anaya JM; Andrews D; Patel HR; Field M; Goodnow C; Arcos-Burgos M, 2015, 'Candidate gene discovery in autoimmunity by using extreme phenotypes, next generation sequencing and whole exome capture', Autoimmunity Reviews, 14, pp. 204 - 209, http://dx.doi.org/10.1016/j.autrev.2014.10.021
2015
Fuchs S; Rensing-Ehl A; Pannicke U; Lorenz MR; Fisch P; Jeelall Y; Rohr J; Speckmann C; Vraetz T; Farmand S; Schmitt-Graeff A; Krüger M; Strahm B; Henneke P; Enders A; Horikawa K; Goodnow C; Schwarz K; Ehl S, 2015, 'Omenn syndrome associated with a functional reversion due to a somatic second-site mutation in CARD11 deficiency', Blood, 126, pp. 1658 - 1669, http://dx.doi.org/10.1182/blood-2015-03-631374
2015
Johar AS; Mastronardi C; Rojas-Villarraga A; Patel HR; Chuah A; Peng K; Higgins A; Milburn P; Palmer S; Silva-Lara MF; Velez JI; Andrews D; Field M; Huttley G; Goodnow C; Anaya JM; Arcos-Burgos M, 2015, 'Novel and rare functional genomic variants in multiple autoimmune syndrome and Sjögren's syndrome', Journal of Translational Medicine, 13, http://dx.doi.org/10.1186/s12967-015-0525-x
2015
Duong JK; Kumar SS; Furlong TJ; Kirkpatrick CM; Graham GG; Greenfield JR; Williams KM; Day RO, 2015, 'The pharmacokinetics of metformin and concentrations of haemoglobin A1C and lactate in Indigenous and non-Indigenous Australians with type 2 diabetes mellitus', British Journal of Clinical Pharmacology, 79, pp. 617 - 623, http://dx.doi.org/10.1111/bcp.12525
2015
Lee P; Swarbrick MM; Greenfield JR, 2015, 'The sum of all browning in FGF21 therapeutics', Cell Metabolism, 21, pp. 795 - 796, http://dx.doi.org/10.1016/j.cmet.2015.05.018
2015
Hillen KM; Gather R; Enders A; Pircher H; Aichele P; Fisch P; Blumenthal B; Schamel WW; Straub T; Goodnow CC; Ehl S, 2015, 'T cell expansion is the limiting factor of virus control in mice with attenuated TCR signaling: Implications for human immunodeficiency', Journal of Immunology, 194, pp. 2725 - 2734, http://dx.doi.org/10.4049/jimmunol.1400328
2015
Liu Y; DeBoer K; de Kretser DM; O’Donnell L; O’Connor AE; Merriner DJ; Okuda H; Whittle B; Jans DA; Efthymiadis A; McLachlan RI; Ormandy CJ; Goodnow CC; Jamsai D; O’Bryan MK, 2015, 'LRGUK-1 Is Required for Basal Body and Manchette Function during Spermatogenesis and Male Fertility', PLoS Genetics, 11, http://dx.doi.org/10.1371/journal.pgen.1005090
2015
Tangye SG; Brink R; Goodnow CC; Phan TG, 2015, 'SnapShot: Interactions between B Cells and T Cells', Cell, 162, pp. 926 - 926.e1, http://dx.doi.org/10.1016/j.cell.2015.07.055
2015
Lim SL; Qu ZP; Kortschak RD; Lawrence DM; Geoghegan J; Hempfling AL; Bergmann M; Goodnow CC; Ormandy CJ; Wong L; Mann J; Scott HS; Jamsai D; Adelson DL; O’Bryan MK, 2015, 'HENMT1 and piRNA Stability Are Required for Adult Male Germ Cell Transposon Repression and to Define the Spermatogenic Program in the Mouse', PLoS Genetics, 11, http://dx.doi.org/10.1371/journal.pgen.1005620
2015
Ramiscal RR; Parish IA; Lee-Young RS; Babon JJ; Blagih J; Pratama A; Martin J; Hawley N; Cappello JY; Nieto PF; Ellyard JI; Kershaw NJ; Sweet RA; Goodnow CC; Jones RG; Febbraio MA; Vinuesa CG; Athanasopoulos V, 2015, 'Attenuation of AMPK signaling by ROQUIN promotes T follicular helper cell formation', eLife, 4, pp. 1 - 22, http://dx.doi.org/10.7554/eLife.08698
2015
Field MA; Cho V; Cook MC; Enders A; Vinuesa CG; Whittle B; Andrews TD; Goodnow CC, 2015, 'Reducing the search space for causal genetic variants with VASP', Bioinformatics, 31, pp. 2377 - 2379, http://dx.doi.org/10.1093/bioinformatics/btv135
2015
Williams RS; Heilbronn LK; Chen DL; Coster A; Greenfield JR; Samocha-Bonet D, 2015, 'Dietary acid load, metabolic acidosis and insulin resistance -
Lessons from cross-sectional and overfeeding studies in humans', Clinical Nutrition, 35, pp. 1084 - 1090, http://dx.doi.org/10.1016/j.clnu.2015.08.002
2015
Field MA; Cho V; Andrews TD; Goodnow CC, 2015, 'Reliably detecting clinically important variants requires both combined variant calls and optimized filtering strategies', PLoS ONE, 10, http://dx.doi.org/10.1371/journal.pone.0143199
2015
Taupin D; Lam W; Rangiah D; McCallum L; Whittle B; Zhang Y; Andrews D; Field M; Goodnow CC; Cook MC, 2015, 'A deleterious RNF43 germline mutation in a severely affected serrated polyposis kindred', Human Genome Variation, 2, pp. 15013, http://dx.doi.org/10.1038/hgv.2015.13
2015
Samocha-Bonet D; Chisholm DJ; Holst JJ; Greenfield JR, 2015, 'L-glutamine and whole protein restore first-phase insulin response and increase glucagon-like peptide-1 in type 2 diabetes patients', Nutrients, 7, pp. 2101 - 2108, http://dx.doi.org/10.3390/nu7042101
2015
Chaudhuri R; Khoo PS; Tonks K; Junutula JR; Kolumam G; Modrusan Z; Samocha-Bonet D; Meoli CC; Hocking S; Fazakerley DJ; Stöckli J; Hoehn KL; Greenfield JR; Yang JYH; James DE, 2015, 'Cross-species gene expression analysis identifies a novel set of genes implicated in human insulin sensitivity', npj Systems Biology and Applications, 1, http://dx.doi.org/10.1038/npjsba.2015.10
2015
Sapkota S; Brien JAE; Greenfield JR; Aslani P, 2015, 'A systematic review of interventions addressing adherence to anti-diabetic medications in patients with type 2 diabetes - Components of interventions', PLoS ONE, 10, http://dx.doi.org/10.1371/journal.pone.0128626
2015
Rahimpour A; Koay HF; Enders A; Clanchy R; Eckle SBG; Meehan B; Chen Z; Whittle B; Liu L; Fairlie DP; Goodnow CC; McCluskey J; Rossjohn J; Uldrich AP; Pellicci DG; Godfrey DI, 2015, 'Identification of phenotypically and functionally heterogeneous mouse mucosal-associated invariant T cells using MR1 tetramers', Journal of Experimental Medicine, 212, pp. 1095 - 1108, http://dx.doi.org/10.1084/jem.20142110
2015
Sabouri Z; Schofield P; Horikawa K; Spierings E; Kipling D; Randall KL; Langley D; Roome B; Vazquez-Lombardi R; Rouet R; Hermes J; Chan TD; Brink R; Dunn-Walters DK; Christ D; Goodnow CC, 2014, 'Redemption of autoantibodies on anergic B cells by variable-region glycosylation and mutation away from self-reactivity', Proceedings of the National Academy of Sciences of the United States of America, 111, http://dx.doi.org/10.1073/pnas.1406974111
2014
Ellyard JI; Jerjen R; Martin JL; Lee AYS; Field MA; Jiang SH; Cappello J; Naumann SK; Andrews TD; Scott HS; Casarotto MG; Goodnow CC; Chaitow J; Pascual V; Hertzog P; Alexander SI; Cook MC; Vinuesa CG, 2014, 'Brief report: Identification of a pathogenic variant in trex1 in early-onset cerebral systemic lupus erythematosus by whole-exome sequencing', Arthritis and Rheumatology, 66, pp. 3382 - 3386, http://dx.doi.org/10.1002/art.38824
2014
Han BY; Wu S; Foo CS; Horton RM; Jenne CN; Watson SR; Whittle B; Goodnow CC; Cyster JG, 2014, 'Zinc finger protein Zfp335 is required for the formation of the naïve T cell compartment', eLife, 3, pp. 1 - 28, http://dx.doi.org/10.7554/eLife.03549
2014
Cho V; Mei Y; Sanny A; Chan S; Enders A; Bertram EM; Tan A; Goodnow CC; Daniel Andrews T, 2014, 'The RNA-binding protein hnRNPLL induces a T cell alternative splicing program delineated by differential intron retention in polyadenylated RNA', Genome Biology, 15, http://dx.doi.org/10.1186/gb-2014-15-1-r26
2014
Enders A; Short A; Miosge LA; Bergmann H; Sontani Y; Bertram EM; Whittle B; Balakishnan B; Yoshida K; Sjollema G; Field MA; Andrews TD; Hagiwara H; Goodnow CC, 2014, 'Zinc-finger protein ZFP318 is essential for expression of IgD, the alternatively spliced Igh product made by mature B lymphocytes', Proceedings of the National Academy of Sciences of the United States of America, 111, pp. 4513 - 4518, http://dx.doi.org/10.1073/pnas.1402739111
2014
Siggs OM; Yates AL; Schlenner S; Liston A; Lesage S; Goodnow CC, 2014, 'A ZAP-70 kinase domain variant prevents thymocyte-positive selection despite signalling CD69 induction', Immunology, 141, pp. 587 - 595, http://dx.doi.org/10.1111/imm.12220
2014
Lee CE; Fulcher DA; Whittle B; Chand R; Fewings N; Field M; Andrews D; Goodnow CC; Cook MC, 2014, 'Autosomal-dominant B-cell deficiency with alopecia due to a mutation in NFKB2 that results in nonprocessable p100', Blood, 124, pp. 2964 - 2972, http://dx.doi.org/10.1182/blood-2014-06-578542
2014
Zammit NW; Malle EK; Walters SN; Goodnow CC; Grey ST, 2014, 'Functional genomics identifies tnfaip3/A20 as a diabetes protective gene', DIABETOLOGIA, 57, pp. S103 - S103, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000344386100229&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2014
Bull KR; Mason T; Rimmer AJ; Crockford TL; Silver KL; Bouriez-Jones T; Hough TA; Chaudhry S; Roberts ISD; Goodnow CC; Cornall RJ, 2014, 'Next-generation sequencing to dissect hereditary nephrotic syndrome in mice identifies a hypomorphic mutation in Lamb2 and models Pierson's syndrome', Journal of Pathology, 233, pp. 18 - 26, http://dx.doi.org/10.1002/path.4308
2014
Altin JA; Daley SR; Howitt J; Rickards HJ; Batkin AK; Horikawa K; Prasad SJ; Nelms KA; Kumar S; Wu LC; Tan SS; Cook MC; Goodnow CC, 2014, 'Ndfip1 mediates peripheral tolerance to self and exogenous antigen by inducing cell cycle exit in responding CD4+ T cells', Proceedings of the National Academy of Sciences of the United States of America, 111, pp. 2067 - 2074, http://dx.doi.org/10.1073/pnas.1322739111
2014
Wang JQ; Jeelall YS; Beutler B; Horikawa K; Goodnow CC, 2014, 'Consequences of the recurrent MYD88L265P somatic mutation for B cell tolerance', Journal of Experimental Medicine, 211, pp. 413 - 426, http://dx.doi.org/10.1084/jem.20131424
2014
Daley SR; Coakley KM; Hu DY; Randall KL; Jenne CN; Limnander A; Myers DR; Polakos NK; Enders A; Roots C; Balakishnan B; Miosge LA; Sjollema G; Bertram EM; Field MA; Shao Y; Daniel Andrews T; Whittle B; Whitney Barnes S; Walker JR; Cyster JG; Goodnow CC; Roose JP, 2013, 'Rasgrp1 mutation increases naïve T-cell CD44 expression and drives mTOR-dependent accumulation of Helios+ T cells and autoantibodies', eLife, 2013, http://dx.doi.org/10.7554/eLife.01020
2013
O'Bryan MK; Clark BJ; McLaughlin EA; D'Sylva RJ; O'Donnell L; Wilce JA; Sutherland J; O'Connor AE; Whittle B; Goodnow CC; Ormandy CJ; Jamsai D, 2013, 'RBM5 Is a Male Germ Cell Splicing Factor and Is Required for Spermatid Differentiation and Male Fertility', PLoS Genetics, 9, http://dx.doi.org/10.1371/journal.pgen.1003628
2013
Daley SR; Hu DY; Goodnow CC, 2013, 'Helios marks strongly autoreactive CD4+ T cells in two major waves of thymic deletion distinguished by induction of PD-1 or NF-κB', Journal of Experimental Medicine, 210, pp. 269 - 285, http://dx.doi.org/10.1084/jem.20121458
2013
Pratama A; Ramiscal RR; Silva DG; Das SK; Athanasopoulos V; Fitch J; Botelho NK; Chang PP; Hu X; Hogan JJ; Maña P; Bernal D; Korner H; Yu D; Goodnow CC; Cook MC; Vinuesa CG, 2013, 'Roquin-2 shares functions with its paralog roquin-1 in the repression of mrnas controlling t follicular helper cells and systemic inflammation', Immunity, 38, pp. 669 - 680, http://dx.doi.org/10.1016/j.immuni.2013.01.011
2013
Bull KR; Rimmer AJ; Siggs OM; Miosge LA; Roots CM; Enders A; Bertram EM; Crockford TL; Whittle B; Potter PK; Simon MM; Mallon AM; Brown SDM; Beutler B; Goodnow CC; Lunter G; Cornall RJ, 2013, 'Unlocking the Bottleneck in Forward Genetics Using Whole-Genome Sequencing and Identity by Descent to Isolate Causative Mutations', PLoS Genetics, 9, http://dx.doi.org/10.1371/journal.pgen.1003219
2013
Teh CE; Horikawa K; Arnold CN; Beutler B; Kucharska EM; Vinuesa CG; Bertram EM; Goodnow CC; Enders A, 2013, 'Heterozygous mis-sense mutations in Prkcb as a critical determinant of anti-polysaccharide antibody formation', Genes and Immunity, 14, pp. 223 - 233, http://dx.doi.org/10.1038/gene.2013.11
2013
Crawford G; Enders A; Gileadi U; Stankovic S; Zhang Q; Lambe T; Crockford TL; Lockstone HE; Freeman A; Arkwright PD; Smart JM; Ma CS; Tangye SG; Goodnow CC; Cerundolo V; Godfrey DI; Su HC; Randall KL; Cornall RJ, 2013, 'DOCK8 is critical for the survival and function of NKT cells', Blood, 122, pp. 2052 - 2061, http://dx.doi.org/10.1182/blood-2013-02-482331
2013
Andrews TD; Sjollema G; Goodnow CC, 2013, 'Understanding the immunological impact of the human mutation explosion', Trends in Immunology, 34, pp. 99 - 106, http://dx.doi.org/10.1016/j.it.2012.12.001
2013
Jamsai D; Clark BJ; Smith SJ; Whittle B; Goodnow CC; Ormandy CJ; O'Bryan MK, 2013, 'A Missense Mutation in the Transcription Factor ETV5 Leads to Sterility, Increased Embryonic and Perinatal Death, Postnatal Growth Restriction, Renal Asymmetry and Polydactyly in the Mouse', PLoS ONE, 8, http://dx.doi.org/10.1371/journal.pone.0077311
2013
Bergmann H; Yabas M; Short A; Miosge L; Barthel N; Teh CE; Roots CM; Bull KR; Jeelall Y; Horikawa K; Whittle B; Balakishnan B; Sjollema G; Bertram EM; Mackay F; Rimmer AJ; Cornall RJ; Field MA; Andrews TD; Goodnow CC; Enders A, 2013, 'B cell survival, surface BCR and BAFFR expression, CD74 metabolism, and CD8- dendritic cells require the intramembrane endopeptidase SPPl2A', Journal of Experimental Medicine, 210, pp. 31 - 40, http://dx.doi.org/10.1084/jem.20121076
2013
Lo JCY; Jamsai D; O'connor A; Borg C; Clark B; Whisstock J; Field M; Adams V; Ishikawa T; Aitken R; Whittle B; Goodnow CC; Ormandy CJ; O'bryan M, 2012, 'RAB-Like 2 Has an Essential Role in Male Fertility, Sperm Intra-Flagellar Transport, and Tail Assembly', PLoS Genetics, 8, pp. e1002969, http://dx.doi.org/10.1371/journal.pgen.1002969
2012
Andrews TD; Whittle B; Field MA; Balakishnan B; Zhang Y; Shao Y; Cho V; Kirk M; Singh M; Xia Y; Hager J; Winslade S; Sjollema G; Beutler B; Enders A; Goodnow CC, 2012, 'Massively parallel sequencing of the mouse exome to accurately identify rare, induced mutations: An immediate source for thousands of new mouse models', Open Biology, 2, http://dx.doi.org/10.1098/rsob.120061
2012
O''Donnell L; Rhodes D; Smith SJ; Merriner DJ; Borg C; Whittle B; O'connor A; Smith L; Mcnally FJ; de Kretser D; Goodnow CC; Ormandy CJ, 2012, 'An essential role for katanin p80 and microtubule severing in male gamete production', PLoS Genetics, 8, pp. e1002698, http://dx.doi.org/10.1371/journal.pgen.1002698
2012
Enders A; Stankovic S; Teh C; Uldrich AP; Yabas M; Juelich T; Altin JA; Frankenreiter S; Bergmann H; Roots CM; Kyparissoudis K; Goodnow CC; Godfrey DI, 2012, 'ZBTB7B (Th-POK) regulates the development of IL-17-producing CD1d-restricted mouse NKT cells', Journal of Immunology, 189, pp. 5240 - 5249, http://dx.doi.org/10.4049/jimmunol.1201486
2012
Altin JA; Goodnow CC; Cook MC, 2012, 'IL-10 +CTLA-4 + Th2 inhibitory cells form in a Foxp3-independent, IL-2-dependent manner from Th2 effectors during chronic inflammation', Journal of Immunology, 188, pp. 5478 - 5488, http://dx.doi.org/10.4049/jimmunol.1102994
2012
Jeelall YS; Wang JQ; Law HD; Domaschenz H; Fung HKH; Kallies A; Nutt SL; Goodnow CC; Horikawa K, 2012, 'Human lymphoma mutations reveal CARD11 as the switch between self-antigen-induced B cell death or proliferation and autoantibody production', Journal of Experimental Medicine, 209, pp. 1907 - 1917, http://dx.doi.org/10.1084/jem.20112744
2012
Hubert FX; Kinkel SA; Davey GM; Phipson B; Mueller SN; Liston A; Proietto AI; Cannon PZF; Forehan S; Smyth GK; Wu L; Goodnow CC; Carbone FR; Scott HS; Heath WR, 2011, 'Aire regulates the transfer of antigen from mTECs to dendritic cells for induction of thymic tolerance', Blood, 118, pp. 2462 - 2472, http://dx.doi.org/10.1182/blood-2010-06-286393
2011
Tze LE; Horikawa K; Domaschenz H; Howard DR; Roots CM; Rigby RJ; Way DA; Ohmura-Hoshino M; Ishido S; Andoniou CE; Degli-Esposti MA; Goodnow CC, 2011, 'CD83 increases MHC II and CD86 on dendritic cells by opposing IL-10 - Driven MARCH1-mediated ubiquitination and degradation', Journal of Experimental Medicine, 208, pp. 149 - 165, http://dx.doi.org/10.1084/jem.20092203
2011
Altin JA; Tian L; Liston A; Bertram EM; Goodnow CC; Cook MC, 2011, 'Decreased T-cell receptor signaling through CARD11 differentially compromises forkhead box protein 3-positive regulatory versus TH2 effector cells to cause allergy', Journal of Allergy and Clinical Immunology, 127, pp. 1277 - 1285.e5, http://dx.doi.org/10.1016/j.jaci.2010.12.1081
2011
Silva DG; Daley SR; Hogan J; Lee SK; Teh CE; Hu DY; Lam KP; Goodnow CC; Vinuesa CG, 2011, 'Anti-islet autoantibodies trigger autoimmune diabetes in the presence of an increased frequency of islet-reactive CD4 T cells', Diabetes, 60, pp. 2102 - 2111, http://dx.doi.org/10.2337/db10-1344
2011
Randall KL; Chang SS; Ma CS; Fung I; Mei Y; Yabas M; Tan A; Arkwright PD; Suwairi WA; Reyes S; Yamazaki-Nakashimada MA; Garcia-Cruz D; Smart J; Picard C; Okada S; Jouanguy E; Casanova J-L; Lambert T; Cornall RJ; Russell S; Oliaro J; Tangye SG; Bertram EM; Goodnow CC, 2011, 'DOCK8 deficiency impairs CD8 T cell survival and function in humans and mice', Journal of Experimental Medicine, 208, pp. 2305 - 2320, http://dx.doi.org/10.1084/jem.20110345
2011
Hoyne GF; Flening E; Yabas M; Teh C; Altin JA; Randall K; Thien CBF; Langdon WY; Goodnow CC, 2011, 'Visualizing the role of Cbl-b in control of islet-reactive CD4 T cells and susceptibility to type 1 diabetes', Journal of Immunology, 186, pp. 2024 - 2032, http://dx.doi.org/10.4049/jimmunol.1002296
2011
Tian L; Altin JA; Makaroff LE; Franckaert D; Cook MC; Goodnow CC; Dooley J; Liston A, 2011, 'Foxp3+ regulatory T cells exert asymmetric control over murine helper responses by inducing Th2 cell apoptosis', Blood, 118, pp. 1845 - 1853, http://dx.doi.org/10.1182/blood-2011-04-346056
2011
Yabas M; Godfrey DI; Goodnow CC; Hoyne GF, 2011, 'Differential requirement for the CD45 splicing regulator hnRNPLL for accumulation of NKT and conventional T cells', PLoS ONE, vol. 6, http://dx.doi.org/10.1371/journal.pone.0026440
2011
Beutler B; Goodnow CC, 2011, 'How host defense is encoded in the mammalian genome', Mammalian Genome, 22, pp. 1 - 5, http://dx.doi.org/10.1007/s00335-010-9312-4
2011
Yabas M; Teh C; Frankenreiter S; Lal D; Roots CM; Whittle B; Andrews DT; Zhang Y; Teoh NC; Sprent J; Tze LE; Kucharska E; Kofler J; Farell GC; Broer S; Goodnow CC; Enders A, 2011, 'ATP11C is critical for the internalization of phosphatidylserine and differentiation of B lymphocytes', Nature Immunology, 12, pp. 441 - 452, http://dx.doi.org/10.1038/ni.2011
2011
Sontani ; Chapman G; Papathanasiou P; Dunwoodie SL; Goodnow CC; Hoyne GF, 2011, 'Cooperation between somatic Ikaros and Notch1 mutations at the inception of T-ALL', Leukemia Research, 35, pp. 1512 - 1519, http://dx.doi.org/10.1016/j.leukres.2011.07.024
2011
Wu Z; Yates AL; Hoyne GF; Goodnow CC, 2010, 'Consequences of increased CD45RA and RC isoforms for TCR signaling and peripheral T cell deficiency resulting from heterogeneous nuclear ribonucleoprotein L-like mutation', Journal of Immunology, 185, pp. 231 - 238, http://dx.doi.org/10.4049/jimmunol.0903625
2010
Randall KL; Lambe T; Johnson A; Treanor B; Kucharska E; Domaschenz H; Whittle B; Tze LE; Enders A; Crockford TL; Bouriez-Jones T; Alston D; Cyster JG; Lenardo MJ; MacKay F; Deenick EK; Tangye SG; Chan TD; Camidge T; Brink R; Vinuesa CG; Batista FD; Cornall RJ; Goodnow CC, 2010, 'Erratum: Dock8 mutations cripple B cell immunological synapses, germinal centers and long-lived antibody production (Nature Immunology (2009) 10 (1283-1291))', Nature Immunology, 11, pp. 644, http://dx.doi.org/10.1038/ni0710-644a
2010
Theodoratos A; Whittle B; Enders A; Tscharke DC; Roots CM; Goodnow CC; Fahrer AM, 2010, 'Mouse strains with point mutations in TAP1 and TAP2', Immunology and Cell Biology, 88, pp. 72 - 78, http://dx.doi.org/10.1038/icb.2009.61
2010
Randall KL; Lambe T; Goodnow CC; Cornall RJ, 2010, 'The essential role of DOCK8 in humoral immunity', Disease Markers, 29, pp. 141 - 150, http://dx.doi.org/10.3233/DMA-2010-0739
2010
Vinuesa CG; Linterman MA; Goodnow CC; Randall KL, 2010, 'T cells and follicular dendritic cells in germinal center B-cell formation and selection', Immunological Reviews, 237, pp. 72 - 89, http://dx.doi.org/10.1111/j.1600-065X.2010.00937.x
2010
Goodnow CC; Vinuesa C; Randall KL; Mackay F; Brink R, 2010, 'Control systems and decision making for antibody production', Nature Immunology, 11, pp. 681 - 688, http://dx.doi.org/10.1038/ni.1900
2010
Johnson AL; Aravind L; Shulzhenko N; Morgun A; Choi SY; Crockford TL; Lambe T; Domaschenz H; Kucharska EM; Zheng L; Vinuesa CG; Lenardo MJ; Goodnow CC; Cornall RJ; Schwartz RH, 2010, 'Erratum: Themis is a member of a new metazoan gene family and is required for the completion of thymocyte positive selection (Nature Immunology (2009) 10 (831-839))', Nature Immunology, 11, pp. 97, http://dx.doi.org/10.1038/ni0110-97a
2010
Zikherman J; Jenne C; Watson S; Doan K; Raschke W; Goodnow CC; Weiss A, 2010, 'CD45-Csk Phosphatase-Kinase Titration Uncouples Basal and Inducible T Cell Receptor Signaling during Thymic Development', Immunity, 32, pp. 342 - 354, http://dx.doi.org/10.1016/j.immuni.2010.03.006
2010
Athanasopoulos V; Barker A; Yu D; Tan AHM; Srivastava M; Contreras N; Wang J; Lam KP; Brown SHJ; Goodnow CC; Dixon NE; Leedman PJ; Saint R; Vinuesa CG, 2010, 'The ROQUIN family of proteins localizes to stress granules via the ROQ domain and binds target mRNAs', FEBS Journal, 277, pp. 2109 - 2127, http://dx.doi.org/10.1111/j.1742-4658.2010.07628.x
2010
Teh CE; Daley SR; Enders A; Goodnow CC, 2010, 'T-cell regulation by casitas B-lineage lymphoma (Cblb) is a critical failsafe against autoimmune disease due to autoimmune regulator (Aire) deficiency', Proceedings of the National Academy of Sciences of the United States of America, 107, pp. 14709 - 14714, http://dx.doi.org/10.1073/pnas.1009209107
2010
Simpson N; Gatenby P; Wilson A; Malik S; Fulcher DA; Tangye SG; Manku H; Vyse TJ; Roncador G; Huttley G; Goodnow CC; Vinuesa C; Cook MC, 2010, 'Expansion of circulating T cells resembling follicular T helper cells is a fixed phenotype that identifies a subset of severe systemic lupus erythematosus', Arthritis Care & Research, 62, pp. 234 - 244, http://dx.doi.org/10.1002/art.25032
2010
Xia Y; Won S; Du X; Lin P; Ross C; La Vine D; Wiltshire S; Leiva G; Vidal SM; Whittle B; Goodnow CC; Koziol J; Moresco EMY; Beutler B, 2010, 'Bulk segregation mapping of mutations in closely related strains of mice', Genetics, 186, pp. 1139 - 1145, http://dx.doi.org/10.1534/genetics.110.121160
2010
Randall KL; Lambe T; Johnson A; Treanor B; Kucharska E; Domaschenz H; Whittle B; Tze LE; Enders A; Crockford TL; Bouriez-Jones T; Alston D; Cyster JG; Lenardo MJ; Mackay F; Deenick EK; Tangye SG; Chan TD; Camidge T; Brink R; Vinuesa C; Batista FD; Cornall RJ; Goodnow CC, 2009, 'Dock8 mutations cripple B cell immunological synapses, germinal centers and long-lived antibody production', Nature Immunology, 10, pp. 1283 - 1291, http://dx.doi.org/10.1038/ni.1820
2009
Chu J; Hong NA; Masuda CA; Jenkins BV; Nelms KA; Goodnow CC; Glynne RJ; Wu H; Masliah E; Joazeiro CAP; Kay SA, 2009, 'A mouse forward genetics screen identifies LISTERIN as an E3 ubiquitin ligase involved in neurodegeneration', Proceedings of the National Academy of Sciences of the United States of America, 106, pp. 2097 - 2103, http://dx.doi.org/10.1073/pnas.0812819106
2009
Nijnik A; Dawson S; Crockford TL; Woodbine L; Visetnoi S; Bennett S; Jones M; Turner GD; Jeggo PA; Goodnow CC; Cornall RJ, 2009, 'Impaired lymphocyte development and antibody class switching and increased malignancy in a murine model of DNA ligase IV syndrome', Journal of Clinical Investigation, 119, pp. 1696 - 1705, http://dx.doi.org/10.1172/JCI32743
2009
Jenne CN; Enders A; Rivera R; Watson SR; Bankovich AJ; Pereira JP; Xu Y; Roots CM; Beilke JN; Banerjee A; Reiner SL; Miller SA; Weinmann AS; Goodnow CC; Lanier LL; Cyster JG; Chun J, 2009, 'T-bet-dependent S1P5 expression in NK cells promotes egress from lymph nodes and bone marrow', Journal of Experimental Medicine, 206, pp. 2469 - 2481, http://dx.doi.org/10.1084/jem.20090525
2009
Goodnow CC; Crosbie J; Adelstein S; Lavoie TB; Smith-Gill SJ; Brink RA; Pritchard-Briscoe H; Wotherspoon JS; Loblay RH; Raphael K; Trent RJ; Basten A, 2009, 'Altered immunoglobulin expression and functional silencing of self-reactive B lymphocytes in transgenic mice.', Journal of immunology (Baltimore, Md. : 1950), 183, pp. 5442 - 5448
2009
Lambe T; Simpson RJ; Dawson S; Bouriez-Jones T; Crockford TL; Lepherd M; Latunde-Dada GO; Robinson H; Raja KB; Campagna DR; Villarreal G; Ellory JC; Goodnow CC; Fleming MD; McKie AT; Cornall RJ, 2009, 'Identification of a Steap3 endosomal targeting motif essential for normal iron metabolism', Blood, 113, pp. 1805 - 1808, http://dx.doi.org/10.1182/blood-2007-11-120402
2009
Johnson AL; Aravind L; Shulzhenko N; Morgun A; Choi SY; Crockford TL; Lambe T; Domaschenz H; Kucharska EM; Zheng L; Vinuesa CG; Lenardo MJ; Goodnow CC; Cornall RJ; Schwartz RH, 2009, 'Themis is a member of a new metazoan gene family and is required for the completion of thymocyte positive selection', Nature Immunology, 10, pp. 831 - 839, http://dx.doi.org/10.1038/ni.1769
2009
Linterman MA; Rigby RJ; Wong R; Silva D; Withers D; Anderson G; Verma NK; Brink R; Hutloff A; Goodnow CC; Vinuesa C, 2009, 'Roquin differentiates the specialized functions of duplicated T cell costimulatory receptor genes CD28 and ICOS', Immunity, 30, pp. 228 - 241, http://dx.doi.org/10.1016/j.immuni.2008.12.015
2009
Goodnow CC; Crosbie J; Adelstein S; Lavoie TB; Smith-Gill SJ; Brink RA; Pritchard-Briscoe H; Wotherspoon JS; Loblay RH; Raphael K; Trent RJ; Basten A, 2009, 'Altered immunoglobulin expression and functional silencing of self-reactive B lymphocytes in transgenic mice (Reprinted from Nature, vol 334, pg 676-682, 1988)', JOURNAL OF IMMUNOLOGY, vol. 183, pp. 5442 - 5448, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000271488500004&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2009
Yu D; Cook MC; Shin DM; Silva DG; Marshall J; Toellner KM; Havran WL; Caroni P; Cooke MP; Morse HC; MacLennan ICM; Goodnow CC; Vinuesa CG, 2008, 'Axon growth and guidance genes identify T-dependent germinal centre B cells', Immunology and Cell Biology, 86, pp. 3 - 14, http://dx.doi.org/10.1038/sj.icb.7100123
2008
Keyes J; Tallack M; Zhan Y; Papathanasiou P; Goodnow CC; Gaensler K; Crossley M; Dekker JP; Perkins A, 2008, 'A mechanism for Ikaros regulation of human globin gene switching', British Journal of Haematology, 141, pp. 398 - 406, http://dx.doi.org/10.1111/j.1365-2141.2008.07065.x
2008
Gosling KM; Goodnow CC; Verma NK; Fahrer AM, 2008, 'Defective T-cell function leading to reduced antibody production in a kleisin-β mutant mouse', Immunology, 125, pp. 208 - 217, http://dx.doi.org/10.1111/j.1365-2567.2008.02831.x
2008
Shiow LR; Roadcap DW; Paris K; Watson SR; Grigorova IL; Lebet T; An J; Xu Y; Jenne CN; Föger N; Sorensen RU; Goodnow CC; Bear JE; Puck JM; Cyster JG, 2008, 'The actin regulator coronin 1A is mutant in a thymic egress-deficient mouse strain and in a patient with severe combined immunodeficiency', Nature Immunology, 9, pp. 1307 - 1315, http://dx.doi.org/10.1038/ni.1662
2008
Wu Z; Jia X; de la Cruz L; Su XC; Marzolf B; Troisch P; Zak D; Hamilton A; Whittle B; Yu D; Sheahan D; Bertram E; Aderem A; Otting G; Goodnow CC; Hoyne GF, 2008, 'Memory T Cell RNA Rearrangement Programmed by Heterogeneous Nuclear Ribonucleoprotein hnRNPLL', Immunity, 29, pp. 863 - 875, http://dx.doi.org/10.1016/j.immuni.2008.11.004
2008
Liu M; Duke JL; Richter DJ; Vinuesa CG; Goodnow CC; Kleinstein SH; Schatz DG, 2008, 'Two levels of protection for the B cell genome during somatic hypermutation', Nature, 451, pp. 841 - 845, http://dx.doi.org/10.1038/nature06547
2008
Yu D; Tan AHM; Hu X; Athanasopoulos V; Simpson N; Silva DG; Hutloff A; Giles KM; Leedman PJ; Lam KP; Goodnow CC; Vinuesa CG, 2008, 'Roquin represses autoimmunity by limiting inducible T-cell co-stimulator messenger RNA (Nature (2007) 450, (299-303))', Nature, 451, pp. 1022, http://dx.doi.org/10.1038/nature06729
2008
Heazlewood CK; Cook MC; Eri R; Price GR; Tauro SB; Taupin D; Thornton DJ; Chin WP; Crockford TL; Cornall RJ; Adams R; Kato M; Nelms KA; Hong NA; Florin THJ; Goodnow CC; McGuckin MA, 2008, 'Aberrant mucin assembly in mice causes endoplasmic reticulum stress and spontaneous inflammation resembling ulcerative colitis', PLoS Medicine, 5, pp. 0440 - 0460, http://dx.doi.org/10.1371/journal.pmed.0050054
2008
Gosling KM; Makaroff LE; Theodoratos A; Kim YH; Whittle B; Rui L; Wu H; Hong NA; Kennedy GC; Fritz JA; Yates AL; Goodnow CC; Fahrer AM, 2007, 'A mutation in a chromosome condensin II subunit, kleisin β, specifically disrupts T cell development', Proceedings of the National Academy of Sciences of the United States of America, 104, pp. 12445 - 12450, http://dx.doi.org/10.1073/pnas.0704870104
2007
Siggs OM; Miosge LA; Yates AL; Kucharska EM; Sheahan D; Brdicka T; Weiss A; Liston A; Goodnow CC, 2007, 'Opposing Functions of the T Cell Receptor Kinase ZAP-70 in Immunity and Tolerance Differentially Titrate in Response to Nucleotide Substitutions', Immunity, 27, pp. 912 - 926, http://dx.doi.org/10.1016/j.immuni.2007.11.013
2007
Goodnow CC, 2007, 'Multistep Pathogenesis of Autoimmune Disease', Cell, 130, pp. 25 - 35, http://dx.doi.org/10.1016/j.cell.2007.06.033
2007
Horikawa K; Martin SW; Pogue SL; Silver K; Peng K; Takatsu K; Goodnow CC, 2007, 'Enhancement and suppression of signaling by the conserved tail of IgG memory-type B cell antigen receptors', Journal of Experimental Medicine, 204, pp. 759 - 769, http://dx.doi.org/10.1084/jem.20061923
2007
Liston A; Siggs OM; Goodnow CC, 2007, 'Tracing the action of IL-2 in tolerance to islet-specific antigen', Immunology and Cell Biology, 85, pp. 338 - 342, http://dx.doi.org/10.1038/sj.icb.7100049
2007
Li G; Vega R; Nelms K; Gekakis N; Goodnow C; McNamara P; Wu H; Hong NA; Glynne R, 2007, 'A role for Alström syndrome protein, Alms1, in kidney ciliogenesis and cellular quiescence', PLoS Genetics, 3, pp. 0009 - 0020, http://dx.doi.org/10.1371/journal.pgen.0030008
2007
Liston A; Hardy K; Pittelkow YE; Wilson SR; Makarof LE; Fahrer AM; Goodnow CC, 2007, 'Impairment of organ-specific T cell negative selection by diabetes susceptibility genes: genomic analysis by mRNA profiling', Genome Biology, 8, pp. R12 - R12, http://dx.doi.org/10.1186/gb-2007-8-1-r12
2007
Nijnik A; Woodbine L; Marchetti C; Dawson S; Lambe T; Liu C; Rodrigues NP; Crockford TL; Cabuy E; Vindigni A; Enver T; Bell JI; Slijepcevic P; Goodnow CC; Jeggo PA; Cornall RJ, 2007, 'DNA repair is limiting for haematopoietic stem cells during ageing', Nature, 447, pp. 686 - 690, http://dx.doi.org/10.1038/nature05875
2007
Goodnow CC, 2007, 'Nossal and Pike 1975: A turning point in the effort to define self-tolerance mechanisms', Journal of Immunology, vol. 179, pp. 5617 - 5618, http://dx.doi.org/10.4049/jimmunol.179.9.5617
2007
Di Yu ; Tan AHM; Hu X; Athanasopoulos V; Simpson N; Silva DG; Hutloff A; Giles KM; Leedman PJ; Lam KP; Goodnow CC; Vinuesa CG, 2007, 'Roquin represses autoimmunity by limiting inducible T-cell co-stimulator messenger RNA', Nature, 450, pp. 299 - 303, http://dx.doi.org/10.1038/nature06253
2007
Goodnow CC, 2006, 'Discriminating microbe from self suffers a double toll', Science, 312, pp. 1606 - 1608, http://dx.doi.org/10.1126/science.1129797
2006
Hoyne GF; Goodnow CC, 2006, 'The use of genomewide ENU mutagenesis screens to unravel complex mammalian traits: Identifying genes that regulate organ-specific and systemic autoimmunity', Immunological Reviews, 210, pp. 27 - 39, http://dx.doi.org/10.1111/j.0105-2896.2006.00363.x
2006
Arsov T; Silva D; O Bryan M; Sainsbury A; Lee NJ; Kennedy C; Manji S; Nelms K; Liu C; Vinuesa C; de Kretser D, 2006, 'Fat Aussie - A new Alstrom syndrome mouse showing a critical role for ALMS1 in obesity, diabetes, and spermatogenesis', Molecular Endocrinology, 20, pp. 1610 - 1622, http://dx.doi.org/10.1210/me.2005-0494
2006
Cook MC; Vinuesa CG; Goodnow CC, 2006, 'ENU-mutagenesis: insight into immune function and pathology', Current Opinion in Immunology, 18, pp. 627 - 633, http://dx.doi.org/10.1016/j.coi.2006.07.011
2006
Bléry M; Tze L; Miosge LA; Jun JE; Goodnow CC, 2006, 'Essential role of membrane cholesterol in accelerated BCR internalization and uncoupling from NF-κB in B cell clonal anergy', Journal of Cell Biology, vol. 174, pp. i5 - i5, http://dx.doi.org/10.1083/jcb1742oia5
2006
Arsov T; Larter CZ; Nolan CJ; Petrovsky N; Goodnow CC; Teoh NC; Yeh MM; Farrell GC, 2006, 'Adaptive failure to high-fat diet characterizes steatohepatitis in Alms1 mutant mice', Biochemical and Biophysical Research Communications, 342, pp. 1152 - 1159, http://dx.doi.org/10.1016/j.bbrc.2006.02.032
2006
Rui L; Healy JI; Blasioli J; Goodnow CC, 2006, 'ERK signaling is a molecular switch integrating opposing inputs from B cell receptor and T cell cytokines to control TLR4-driven plasma cell differentiation', Journal of Immunology, 177, pp. 5337 - 5346, http://dx.doi.org/10.4049/jimmunol.177.8.5337
2006
Nijnik A; Ferry H; Lewis G; Rapsomaniki E; Leung JCH; Daser A; Lambe T; Goodnow CC; Cornall RJ, 2006, 'Spontaneous B cell hyperactivity in autoimmune-prone MRL mice', International Immunology, 18, pp. 1127 - 1137, http://dx.doi.org/10.1093/intimm/dxl047
2006
Gray DHD; Seach N; Ueno T; Milton MK; Liston A; Lew AM; Goodnow CC; Boyd RL, 2006, 'Developmental kinetics, turnover, and stimulatory capacity of thymic epithelial cells', Blood, 108, pp. 3777 - 3785, http://dx.doi.org/10.1182/blood-2006-02-004531
2006
Kennedy CL; O'Connor AE; Sanchez-Partida LG; Holland MK; Goodnow CC; de Kretser DM; O'Bryan MK, 2006, 'A repository of ENU mutant mouse lines and their potential for male fertility research', Molecular Human Reproduction, 11, pp. 871 - 880, http://dx.doi.org/10.1093/molehr/gah251
2006
Manderson AP; Quah B; Botto M; Goodnow CC; Walport MJ; Parish CR, 2006, 'A novel mechanism for complement activation at the surface of B cells following antigen binding', Journal of Immunology, vol. 177, pp. 5155 - 5162, http://dx.doi.org/10.4049/jimmunol.177.8.5155
2006
Alexander WS; Viney EM; Zhang JG; Metcalf D; Kauppi M; Hyland CD; Carpinelli MR; Stevenson W; Croker BA; Hilton AA; Ellis S; Selan C; Nandurkar HH; Goodnow CC; Kile BT; Nicola NA; Roberts AW; Hilton DJ, 2006, 'Thrombocytopenia and kidney disease in mice with a mutation in the C1galt1 gene', Proceedings of the National Academy of Sciences of the United States of America, 103, pp. 16442 - 16447, http://dx.doi.org/10.1073/pnas.0607872103
2006
Rui L; Goodnow CC, 2006, 'Lymphoma and the control of B cell growth and differentiation', Current Molecular Medicine, 6, pp. 291 - 308, http://dx.doi.org/10.2174/156652406776894563
2006
Bléry M; Tze L; Miosge LA; Jun JE; Goodnow CC, 2006, 'Essential role of membrane cholesterol in accelerated BCR internalization and uncoupling from NF-κB in B cell clonal anergy', Journal of Experimental Medicine, 203, pp. 1773 - 1783, http://dx.doi.org/10.1084/jem.20060552
2006
Goodnow CC; Sprent J; Barbara BF; Vinuesa CG, 2005, 'Cellular and genetic mechanisms of self tolerance and autoimmunity', Nature, 435, pp. 590 - 597, http://dx.doi.org/10.1038/nature03724
2005
Vinuesa CG; Cook MC; Angelucci C; Athanasopoulos V; Rui L; Hill KM; Yu D; Domaschenz H; Whittle B; Lambe T; Roberts IS; Copley RR; Bell JI; Cornall RJ; Goodnow CC, 2005, 'A RING-type ubiquitin ligase family member required to repress follicular helper T cells and autoimmunity', Nature, 435, pp. 452 - 458, http://dx.doi.org/10.1038/nature03555
2005
Ferry H; Cockford TL; Silver K; Rust N; Goodnow CC; Cornall R, 2005, 'Analysis of Lyn/CD22 double-deficient B cells in vivo demonstrates Lyn- and CD22-independent pathways affecting BCR regulation and B cell survival', European Journal of Immunology, 35, pp. 3655 - 3663, http://dx.doi.org/10.1002/eji.200535247
2005
Liston A; Lesage S; Gray DHD; Boyd RL; Goodnow CC, 2005, 'Genetic lesions in T-cell tolerance and thresholds for autoimmunity', Immunological Reviews, 204, pp. 87 - 101, http://dx.doi.org/10.1111/j.0105-2896.2005.00253.x
2005
Miosge LA; Goodnow CC, 2005, 'Genes, pathways and checkpoints in lymphocyte development and homeostasis', Immunology and Cell Biology, 83, pp. 318 - 335, http://dx.doi.org/10.1111/j.1440-1711.2005.01353.x
2005
Ferry H; Crockford TL; Silver K; Rust N; Goodnow CC; Cornall RJ, 2005, 'Erratum: Analysis of Lyn/CD22 double-deficient B cells in vivo demonstrates Lyn- and CD22- independent pathways affecting BCR regulation and B cell survival (European Journal of Immunology (2005) vol. 35 (12) (3714) 10.1002/eji.200535247)', European Journal of Immunology, vol. 35, pp. 3714, http://dx.doi.org/10.1002/eji.255590598
2005
Vinuesa CG; Goodnow CC, 2004, 'Illuminating autoimmune regulators through controlled variation of the mouse genome sequence', Immunity, 20, pp. 669 - 679, http://dx.doi.org/10.1016/j.immuni.2004.05.012
2004
Liston A; Gray DHD; Lesage S; Fletcher AL; Wilson J; Webster KE; Scott HS; Boyd RL; Peltonen L; Goodnow CC, 2004, 'Gene dosage-limiting role of Aire in thymic expression, clonal deletion, and organ-specific autoimmunity', Journal of Experimental Medicine, 200, pp. 1015 - 1026, http://dx.doi.org/10.1084/jem.20040581
2004
Liston A; Lesage S; Gray DHD; O reilly LA; Strasser A; Fahrer AM; Boyd RL; Wilson J; Baxter AG; Gallo E; Crabtree GR; Peng K; Wilson SR; Goodnow CC, 2004, 'Generalised resistance to thymic deletion in the NODmouse: a polygenic trait characterized by defective induction of Bim', Immunity, 21, pp. 817 - 830, http://dx.doi.org/10.1016/j.immuni.2004.10.014
2004
Jun JE; Wilson LE; Vinuesa CG; Lesage S; Blery M; Miosge LA; Cook MC; Kucharska EM; Hara H; Penninger JM; Domashenz H; Hong NA; Glynne RJ; Nelms KA; Goodnow CC, 2003, 'Identifying the MAGUK protein Carma-1 as a central regulator of humoral immune responses and atopy by genome-wide mouse mutagenesis', Immunity, 18, pp. 751 - 762, http://dx.doi.org/10.1016/S1074-7613(03)00141-9
2003
Liston A; Lesage S; Wilson J; Peltonen L; Goodnow CC, 2003, 'Aire regulates negative selection of organ-specific T cells', Nature Immunology, 4, pp. 350 - 354, http://dx.doi.org/10.1038/ni906
2003
Papathanasiou P; Perkins AC; Cobb BS; Ferrini R; Sridharan R; Hoyne GF; Nelms KA; Smale ST; Goodnow CC, 2003, 'Widespread failure of hematolymphoid differentiation caused by a recessive niche-filling allele of the ikaros transcription factor', Immunity, 19, pp. 131 - 144, http://dx.doi.org/10.1016/S1074-7613(03)00168-7
2003
Jun JE; Goodnow CC, 2003, 'Scaffolding of antigen receptors for immunogenic versus tolerogenic signaling', Nature Immunology, 4, pp. 1057 - 1064, http://dx.doi.org/10.1038/ni1001
2003
Rui L; Vinuesa CG; Blasioli J; Goodnow CC, 2003, 'Resistance to CpG DNA-induced autoimmunity through tolerogenic B cell antigen receptor ERK signaling', Nature Immunology, 4, pp. 594 - 600, http://dx.doi.org/10.1038/ni924
2003
Loy AL; Goodnow CC, 2002, 'Novel approaches for identifying genes regulating lymphocyte development and function', Current Opinion in Immunology, vol. 14, pp. 260 - 265, http://dx.doi.org/10.1016/S0952-7915(02)00331-X
2002
Prasad SJ; Goodnow CC, 2002, 'Intrinsic in vitro abnormalities in dendritic cell generation caused by non-MHC non-obese diabetic genes', Immunology and Cell Biology, 80, pp. 198 - 206, http://dx.doi.org/10.1046/j.1440-1711.2002.01074.x
2002
Martin SW; Goodnow CC, 2002, 'Burst-enhancing role of the IgG membrane tail as a molecular determinant of memory', Nature Immunology, 3, pp. 182 - 188, http://dx.doi.org/10.1038/ni752
2002
Lesage S; Hartley SB; Akkaraju S; Wilson J; Townsend M; Goodnow CC, 2002, 'Failure to censor forbidden clones of CD4 T cells in autoimmune diabetes', Journal of Experimental Medicine, 196, pp. 1175 - 1188, http://dx.doi.org/10.1084/jem.20020735
2002
Miosge LA; Blasioli J; Blery M; Goodnow CC, 2002, 'Analysis of an ethylnitrosourea-generated mouse mutation defines a cell intrinsic role of nuclear factor κB2 in regulating circulating B cell numbers', Journal of Experimental Medicine, 196, pp. 1113 - 1119, http://dx.doi.org/10.1084/jem.20020959
2002
Prasad SJ; Goodnow CC, 2002, 'Cell-intrinsic effects of non-MHC NOD genes on dendritic cell generation in vivo', International Immunology, 14, pp. 677 - 684, http://dx.doi.org/10.1093/intimm/dxf034
2002
Vinuesa CG; Goodnow CC, 2002, 'DNA drives autoimmunity', Nature, 416, pp. 595 - 598, http://dx.doi.org/10.1038/416595a
2002
Nelms KA; Goodnow CC, 2001, 'Genome-wide ENU mutagenesis to reveal immune regulators', Immunity, 15, pp. 409 - 418, http://dx.doi.org/10.1016/S1074-7613(01)00199-6
2001
Goodnow CC, 2001, 'Pathways for self-tolerance and the treatment of autoimmune diseases', Lancet, 357, pp. 2115 - 2121, http://dx.doi.org/10.1016/S0140-6736(00)05185-0
2001
Lesage S; Goodnow CC, 2001, 'Organ-specific autoimmune disease: A deficiency of tolerogenic stimulation', Journal of Experimental Medicine, vol. 194, http://dx.doi.org/10.1084/jem.194.5.F31
2001
Goodnow CC; Glynne R; Akkaraju S; Rayner J; Mack D; Healy JI; Chaudhry S; Miosge L; Wilson L; Papathanasiou P; Loy A, 2001, 'Autoimmunity, self-tolerance and immune homeostasis: From whole animal phenotypes to molecular pathways', Advances in Experimental Medicine and Biology, 490, pp. 33 - 40, http://dx.doi.org/10.1007/978-1-4615-1243-1_4
2001
Fahrer AM; Bazan FJ; Papathanasiou P; Nelms KA; Goodnow CC, 2001, 'A genomic view of immunology', Nature, 409, pp. 836 - 838, http://dx.doi.org/10.1038/35057020
2001
Townsend SE; Goodnow CC; Cornall RJ, 2001, 'Single epitope multiple staining to detect ultralow frequency B cells', Journal of Immunological Methods, 249, pp. 137 - 146, http://dx.doi.org/10.1016/S0022-1759(00)00352-5
2001
Nadeau JH; Balling R; Barsh G; Beier D; Brown SDM; Bucan M; Camper S; Carlson G; Copeland N; Eppig J; Fletcher C; Frankel WN; Ganten D; Goldowitz D; Goodnow C; Guenet JL; Hicks G; De Angelis MH; Jackson I; Jacob HJ; Jenkins N; Johnson D; Justice M; Kay S; Kingsley D; Lehrach H; Magnuson T; Meisler M; Poustka A; Rinchik EM; Rossant J; Russell LB; Schimenti J; Shiroishi T; Skarnes WC; Soriano P; Stanford W; Takahashi JS; Wurst W; Zimmer A, 2001, 'Sequence interpretation: Functional annotation of mouse genome sequences', Science, 291, pp. 1251 - 1255, http://dx.doi.org/10.1126/science.1058244
2001
Glynne R; Akkaraju S; Healy JI; Rayner J; Goodnow CC; Mack DH, 2000, 'Erratum: How self-tolerance and the immunosuppressive drug FK506 prevent B-cell mitogenesis (Nature (2000) 403: (672-676))', Nature, 407, pp. 413, http://dx.doi.org/10.1038/35030187
2000
Glynne R; Akkaraju S; Healy JI; Rayner J; Goodnow CC; Mack DH, 2000, 'How self-tolerance and the immunosuppressive drug FK506 prevent B-cell mitogenesis (vol 403, pg 672, 2000)', NATURE, 407, pp. 413 - +, http://dx.doi.org/10.1038/35030187
2000
Martin S; Goodnow C, 2000, 'Memory needs no reminders', Nature, 407, pp. 576 - 577, http://dx.doi.org/10.1038/35036673
2000
Weintraub BC; Jun JE; Bishop AC; Shokat KM; Thomas ML; Goodnow CC, 2000, 'Entry of B cell receptor into signaling domains is inhibited in tolerant B cells', Journal of Experimental Medicine, vol. 191, pp. 1443 - 1448, http://dx.doi.org/10.1084/jem.191.8.1443
2000
Glynne R; Ghandour G; Rayner J; Mack DH; Goodnow CC, 2000, 'B-lymphocyte quiescence, tolerance and activation as viewed by global gene expression profiling on microarrays', Immunological Reviews, 176, pp. 216 - 246, http://dx.doi.org/10.1034/j.1600-065X.2000.00614.x
2000
Glynne RJ; Ghandour G; Goodnow CC, 2000, 'Genomic-scale gene expression analysis of lymphocyte growth, tolerance and malignancy', Current Opinion in Immunology, vol. 12, pp. 210 - 214, http://dx.doi.org/10.1016/S0952-7915(99)00076-X
2000
Pogue SL; Goodnow CC, 2000, 'Gene dose-dependent maturation and receptor editing of B cells expressing immunoglobulin (Ig)G1 or IgM/IgG1 tail antigen receptors', Journal of Experimental Medicine, 191, pp. 1031 - 1043, http://dx.doi.org/10.1084/jem.191.6.1031
2000
Glynne R; Akkaraju S; Healy JI; Rayner J; Goodnow CC; Mack DH, 2000, 'How self-tolerance and the immunosuppressive drug FK506 prevent B-cell mitogenesis', Nature, 403, pp. 672 - 676, http://dx.doi.org/10.1038/35001102
2000
Cornall RJ; Cheng AM; Pawson T; Goodnow CC, 2000, 'Role of Syk in B-cell development and antigen-receptor signaling', Proceedings of the National Academy of Sciences of the United States of America, 97, pp. 1713 - 1718, http://dx.doi.org/10.1073/pnas.97.4.1713
2000
Townsend SE; Weintraub BC; Goodnow CC, 1999, 'Growing up on the streets: Why B-cell development differs from T-cell development', Immunology Today, 20, pp. 217 - 220, http://dx.doi.org/10.1016/S0167-5699(98)01440-6
1999
Cornall RJ; Cyster JG; Hibbs ML; Dunn AR; Otipoby KL; Clark EA; Goodnow CC, 1998, 'Polygenic autoimmune traits: Lyn, CD22, and SHP-1 are limiting elements of a biochemical pathway regulating BCR signaling and selection', Immunity, 8, pp. 497 - 508, http://dx.doi.org/10.1016/S1074-7613(00)80554-3
1998
Healy JI; Dolmetsch RE; Lewis RS; Goodnow CC, 1998, 'Quantitative and qualitative control of antigen receptor signalling in tolerant B lymphocytes.', Novartis Foundation symposium, 215
1998
Rathmell JC; Fournier S; Weintraub BC; Allison JP; Goodnow CC, 1998, 'Repression of B7.2 on self-reactive B cells is essential to prevent proliferation and allow Fas-mediated deletion by CD4+ T cells', Journal of Experimental Medicine, 188, pp. 651 - 659, http://dx.doi.org/10.1084/jem.188.4.651
1998
Ying H; Healy JI; Goodnow CC; Parnes JR, 1998, 'Regulation of mouse CD72 gene expression during B lymphocyte development', Journal of Immunology, 161, pp. 4760 - 4767
1998
Rathmell JC; Goodnow CC, 1998, 'The in vivo balance between B cell clonal expansion and elimination is regulated by CD95 both on B cells and in their micro-environment', Immunology and Cell Biology, 76, pp. 387 - 394, http://dx.doi.org/10.1046/j.1440-1711.1998.00774.x
1998
Prodeus AP; Goerg S; Shen LM; Pozdnyakova OO; Chu L; Alicot EM; Goodnow CC; Carroll MC, 1998, 'A critical role for complement in maintenance of self-tolerance', Immunity, 9, pp. 721 - 731, http://dx.doi.org/10.1016/S1074-7613(00)80669-X
1998
Fischer MB; Goerg S; Shen LM; Prodeus AP; Goodnow CC; Kelsoe G; Carroll MC, 1998, 'Dependence of germinal center B cells on expression of CD21/CD35 for survival', Science, 280, pp. 582 - 585, http://dx.doi.org/10.1126/science.280.5363.582
1998
Fang W; Weintraub BC; Dunlap B; Garside P; Pape KA; Jenkins MK; Goodnow CC; Mueller DL; Behrens TW, 1998, 'Self-reactive B lymphocytes overexpressing Bcl-x(L) escape negative selection and are tolerized by clonal anergy and receptor editing', Immunity, 9, pp. 35 - 45, http://dx.doi.org/10.1016/S1074-7613(00)80586-5
1998
Schmidt KN; Hsu CW; Griffin CT; Goodnow CC; Cyster JG, 1998, 'Spontaneous follicular exclusion of SHP1-deficient B cells is conditional on the presence of competitor wild-type B cells', Journal of Experimental Medicine, vol. 187, pp. 929 - 937, http://dx.doi.org/10.1084/jem.187.6.929
1998
Cornall RJ; Goodnow CC, 1998, 'B cell antigen receptor signalling in the balance of tolerance and immunity.', Novartis Foundation symposium, 215
1998
Weintraub BC; Goodnow CC, 1998, 'Immune responses: Costimulatory receptors have their say', Current Biology, 8, http://dx.doi.org/10.1016/s0960-9822(07)00365-x
1998
Townsend SE; Goodnow CC, 1998, 'Abortive proliferation of rare T cells induced by direct or indirect antigen presentation by rare B cells in vivo', Journal of Experimental Medicine, 187, pp. 1611 - 1621, http://dx.doi.org/10.1084/jem.187.10.1611
1998
Goodnow CC, 1998, 'Cancer immunotherapy: New leads on an elusive goal', Medical Journal of Australia, vol. 169, pp. 570 - 571, http://dx.doi.org/10.5694/j.1326-5377.1998.tb123418.x
1998
Goodnow CC; Cyster JG, 1997, 'Lymphocyte homing: The scent of a follicle', Current Biology, 7, http://dx.doi.org/10.1016/s0960-9822(06)00105-9
1997
Timmerman LA; Healy JI; Ho SN; Chen L; Goodnow CC; Crabtree GR, 1997, 'Redundant expression but selective utilization of nuclear factor of activated T cells family members', Journal of Immunology, 159, pp. 2735 - 2740
1997
Akkaraju S; Ho WY; Leong D; Canaan K; Davis MM; Goodnow CC, 1997, 'A range of CD4 T cell tolerance: Partial inactivation to organ-specific antigen allows nondestructive thyroiditis or insulitis', Immunity, 7, pp. 255 - 271, http://dx.doi.org/10.1016/S1074-7613(00)80528-2
1997
Macaulay AE; Dekruyff RH; Goodnow CC; Umetsu DT, 1997, 'Antigen-Specific B Cells Preferentially Induce CD4+ T Cells to Produce IL-4', Journal of Immunology, 158, pp. 4171 - 4179
1997
Inaoki M; Sato S; Weintraub BC; Goodnow CC; Tedder TF, 1997, 'CD19-regulated signaling thresholds control peripheral tolerance and autoantibody production in B lymphocytes', Journal of Experimental Medicine, 186, pp. 1923 - 1931, http://dx.doi.org/10.1084/jem.186.11.1923
1997
Cyster JG; Goodnow CC, 1997, 'Tuning antigen receptor signaling by CD22: Integrating cues from antigens and the microenvironment', Immunity, 6, pp. 509 - 517, http://dx.doi.org/10.1016/S1074-7613(00)80339-8
1997
Goodnow CC, 1997, 'Glimpses into the balance between immunity and self-tolerance', CIBA Foundation Symposia, pp. 190 - 207
1997
Akkaraju S; Canaan K; Goodnow CC, 1997, 'Self-reactive B cells are not eliminated or inactivated by autoantigen expressed on thyroid epithelial cells', Journal of Experimental Medicine, 186, pp. 2005 - 2012, http://dx.doi.org/10.1084/jem.186.12.2005
1997
Dolmetsch RE; Lewis RS; Goodnow CC; Healy JI, 1997, 'Differential activation of transcription factors induced by Ca2+ response amplitude and duration', Nature, 386, pp. 855 - 858, http://dx.doi.org/10.1038/386855a0
1997
Dolmetsch RE; Lewis RS; Goodnow CC; Healy JI, 1997, 'Erratum: Differential activation of transcription factors induced by Ca2+ response amplitude and duration (Nature (1997) 386 (855-858))', Nature, 388, pp. 308, http://dx.doi.org/10.1038/40912
1997
Healy JI; Dolmetsch RE; Timmerman LA; Cyster JG; Thomas ML; Crabtree GR; Lewis RS; Goodnow CC, 1997, 'Different nuclear signals are activated by the B cell receptor during positive versus negative signaling', Immunity, 6, pp. 419 - 428, http://dx.doi.org/10.1016/S1074-7613(00)80285-X
1997
Goodnow CC, 1997, 'Chance encounters and organized rendezvous', Immunological Reviews, vol. 156, pp. 5 - 10, http://dx.doi.org/10.1111/j.1600-065X.1997.tb00954.x
1997
Fournier S; Rathmell JC; Goodnow CC; Allison JP, 1997, 'T cell-mediated elimination of B7.2 transgenic B cells', Immunity, 6, pp. 327 - 339, http://dx.doi.org/10.1016/S1074-7613(00)80335-0
1997
Townsend SE; Goodnow CC, 1996, 'T cell/B cell collaboration in the lysozyme system: An in vivo model', FASEB Journal, vol. 10
1996
Cyster J; Thomas M; Goodnow C, 1996, 'Signals regulating B lymphocyte migration and survival in lymphoid tissues', FASEB Journal, vol. 10
1996
Goodnow CC, 1996, 'Balancing immunity and tolerance: Deleting and tuning lymphocyte repertoires', Proceedings of the National Academy of Sciences of the United States of America, 93, pp. 2264 - 2271, http://dx.doi.org/10.1073/pnas.93.6.2264
1996
Cyster JG; Healy JI; Kishihara K; Mak TW; Thomas ML; Goodnow CC, 1996, 'Regulation of B-lymphocyte negative and positive selection by tyrosine phosphatase CD45', Nature, 381, pp. 325 - 328, http://dx.doi.org/10.1038/381325a0
1996
Dempsey PW; Allison MED; Akkaraju S; Goodnow CC; Fearon DT, 1996, 'C3d of complement as a molecular adjuvant: Bridging innate and acquired immunity', Science, 271, pp. 348 - 350, http://dx.doi.org/10.1126/science.271.5247.348
1996
Janeway CA; Goodnow CC; Medzhitov R, 1996, 'Immunological tolerance: Danger - Pathogen on the premises!', Current Biology, 6, pp. 519 - 522, http://dx.doi.org/10.1016/s0960-9822(02)00531-6
1996
Rathmell JC; Townsend SE; Xu JC; Flavell RA; Goodnow CC, 1996, 'Expansion or elimination of B cells in vivo: Dual roles for CD40- and Fas (CD95)-ligands modulated by the B cell antigen receptor', Cell, 87, pp. 319 - 329, http://dx.doi.org/10.1016/S0092-8674(00)81349-5
1996
Liblau RS; Tisch R; Shokat K; Yang XD; Dumont N; Goodnow CC; Mcdevitt HO, 1996, 'Intravenous injection of soluble antigen induces thymic and peripheral T-cell apoptosis', Proceedings of the National Academy of Sciences of the United States of America, 93, pp. 3031 - 3036, http://dx.doi.org/10.1073/pnas.93.7.3031
1996
Rathmell JC; Cooke MP; Ho WY; Grein J; Townsend SE; Davis MM; Goodnow CC, 1995, 'CD95 (Fas)-dependent elimination of self-reactive B cells upon interaction with CD4+T cells', Nature, 376, pp. 181 - 184, http://dx.doi.org/10.1038/376181a0
1995
Shokat KM; Goodnow CC, 1995, 'Antigen-induced B-cell death and elimination during germinal-centre immune responses', Nature, 375, pp. 334 - 338, http://dx.doi.org/10.1038/375334a0
1995
Cyster JG; Goodnow CC, 1995, 'Pertussis toxin inhibits migration of b and t lymphocytes into splenic white pulp cords', Journal of Experimental Medicine, 182, pp. 581 - 586, http://dx.doi.org/10.1084/jem.182.2.581
1995
Cyster JG; Goodnow CC, 1995, 'Protein tyrosine phosphatase 1C negatively regulates antigen receptor signaling in B lymphocytes and determines thresholds for negative selection', Immunity, 2, pp. 13 - 24, http://dx.doi.org/10.1016/1074-7613(95)90075-6
1995
Cyster JG; Goodnow CC, 1995, 'Antigen-induced exclusion from follicles and anergy are separate and complementary processes that influence peripheral B cell fate', Immunity, 3, pp. 691 - 701, http://dx.doi.org/10.1016/1074-7613(95)90059-4
1995
Brink R; Goodnow CC; Basten A, 1995, 'IgD expression on B cells is more efficient than IgM but both receptors are functionally equivalent in up‐regulation CD80/CD86 co‐stimulatory molecules', European Journal of Immunology, 25, pp. 1980 - 1984, http://dx.doi.org/10.1002/eji.1830250727
1995
Goodnow CC; Cyster JG; Hartley SB; Bell SE; Cooke MP; Healy JI; Akkaraju S; Rathmell JC; Pogue SL; Shokat KP, 1995, 'Self-tolerance checkpoints in B lymphocyte development', Advances in Immunology, 59, pp. 279 - 368, http://dx.doi.org/10.1016/s0065-2776(08)60633-1
1995
Rathmell JC; Goodnow CC, 1995, 'Autoimmunity: The Fas track', Current Biology, 5, pp. 1218 - 1221, http://dx.doi.org/10.1016/S0960-9822(95)00241-7
1995
Lund FE; Solvason NW; Cooke MP; Heath AW; Grimaldi JC; Parkhouse RME; Goodnow CC; Howard MC, 1995, 'Signaling through murine CD38 is impaired in antigen receptor‐unresponsive B cells', European Journal of Immunology, vol. 25, pp. 1338 - 1345, http://dx.doi.org/10.1002/eji.1830250531
1995
Cornall RJ; Goodnow CC; Cyster JG, 1995, 'The regulation of self-reactive B cells', Current Opinion in Immunology, 7, pp. 804 - 811, http://dx.doi.org/10.1016/0952-7915(95)80052-2
1995
Hartley SB; Goodnow CC, 1994, 'Censoring of self-reactive b cells with a range of receptor affinities in transgenic mice expressing heavy chains for a lysozyme-specific antibody', International Immunology, vol. 6, pp. 1417 - 1425, http://dx.doi.org/10.1093/intimm/6.9.1417
1994
Ho WY; Cooke MP; Goodnow CC; Davis MM, 1994, 'Resting and anergic B cells are defective in CD28-dependent costimulation of naive CD4+ T cells', Journal of Experimental Medicine, 179, pp. 1539 - 1549, http://dx.doi.org/10.1084/jem.179.5.1539
1994
Cooke MP; Heath AW; Shokat KM; Zeng Y; Finkelman FD; Linsley PS; Howard M; Goodnow CC, 1994, 'Immunoglobulin signal transduction guides the specificity of B cell-T cell interactions and is blocked in tolerant self-reactive B cells', Journal of Experimental Medicine, 179, pp. 425 - 438, http://dx.doi.org/10.1084/jem.179.2.425
1994
Cyster JG; Hartley SB; Goodnow CC, 1994, 'Competition for follicular niches excludes self-reactive cells from the recirculating B-cell repertoire', Nature, 371, pp. 389 - 395, http://dx.doi.org/10.1038/371389a0
1994
Lenschow DJ; Sperling AI; Cooke MP; Freeman G; Rhee L; Decker DC; Gray G; Nadler LM; Goodnow CC; Bluestone JA, 1994, 'Differential up-regulation of the B7-1 and B7-2 costimulatory molecules after Ig receptor engagement by antigen', Journal of Immunology, 153, pp. 1990 - 1997
1994
Rathmell JC; Goodnow CC, 1994, 'Effects of the lpr mutation on elimination and inactivation of self- reactive B cells', Journal of Immunology, 153, pp. 2831 - 2842
1994
Brink R; Fulcher DA; Goodnow CC; Basten A, 1994, 'Differential regulation of early and late stages of B lymphocyte development by the μ and δ membrane heavy chains of Ig', International Immunology, vol. 6, pp. 1905 - 1916, http://dx.doi.org/10.1093/intimm/6.12.1905
1994
Pogue SL; Goodnow CC, 1994, 'Ig heavy chain extracellular spacer confers unique glycosylation of the Mb-1 component of the B cell antigen receptor complex', Journal of Immunology, 152, pp. 3925 - 3434
1994
Bell SE; Goodnow CC, 1994, 'A selective defect in IgM antigen receptor synthesis and transport causes loss of cell surface IgM expression on tolerant B lymphocytes', EMBO Journal, 13, pp. 816 - 826, http://dx.doi.org/10.1002/j.1460-2075.1994.tb06324.x
1994
Hartley SB; Cooke MP; Fulcher DA; Harris AW; Cory S; Basten A; Goodnow CC, 1993, 'Elimination of self-reactive B lymphocytes proceeds in two stages: Arrested development and cell death', Cell, 72, pp. 325 - 335, http://dx.doi.org/10.1016/0092-8674(93)90111-3
1993
Goodnow CC, 1992, 'Transgenic mice and analysis of B-cell tolerance', Annual Review of Immunology, 10, pp. 489 - 518, http://dx.doi.org/10.1146/annurev.iy.10.040192.002421
1992
Goodnow CC, 1992, 'B-cell tolerance', Current Opinion in Immunology, vol. 4, pp. 703 - 710, http://dx.doi.org/10.1016/0952-7915(92)90049-K
1992
Nossal GJV; Herold KC; Goodnow CC, 1992, 'Autoimmune tolerance and Type 1 (insulin-dependent) diabetes mellitus', Diabetologia, 35, http://dx.doi.org/10.1007/BF00586279
1992
Brink R; Goodnow CC; Crosbie J; Adams E; Eris J; Mason DY; Hartley SB; Basten A, 1992, 'Immunoglobulin M and D Antigen Receptors are Both Capable of Mediating B Lymphocyte Activation, Deletion, or Anergy After Interaction with Specific Antigen', Journal of Experimental Medicine, 176, pp. 991 - 1005, http://dx.doi.org/10.1084/jem.176.4.991
1992
MASON DY; JONES M; GOODNOW CC, 1992, 'DEVELOPMENT AND FOLLICULAR LOCALIZATION OF TOLERANT LYMPHOCYTES-B IN LYSOZYME ANTILYSOZYME IGM IGD TRANSGENIC MICE', INTERNATIONAL IMMUNOLOGY, 4, pp. 163 - 175, http://dx.doi.org/10.1093/intimm/4.2.163
1992
Basten A; Brink R; Peake P; Adams E; Crosbie J; Hartley S; Goodnow CC, 1991, 'Self Tolerance in the B‐Cell Repertoire', Immunological Reviews, 122, pp. 5 - 19, http://dx.doi.org/10.1111/j.1600-065X.1991.tb00593.x
1991
Goodnow CC; Brink R; Adams E, 1991, 'Breakdown of self-tolerance in anergic B lymphocytes', Nature, 352, pp. 532 - 536, http://dx.doi.org/10.1038/352532a0
1991
Brooks A; Hartley S; Kjer-Nielsen L; Perera J; Goodnow CC; Basten A; McCluskey J, 1991, 'Class II-restricted presentation of an endogenously derived immunodominant T-cell determinant of hen egg lysozyme', Proceedings of the National Academy of Sciences of the United States of America, 88, pp. 3290 - 3294, http://dx.doi.org/10.1073/pnas.88.8.3290
1991
Basten A; Brink R; Peake P; Adams E; Crosbie J; Hartley S; Goodnow CC, 1991, 'Self tolerance in the B-cell repertoire', Immunological Reviews
1991
Adelstein S; Pritchard-Briscoe H; Anderson TA; Crosbie J; Gammon G; Loblay RH; Basten A; Goodnow CC, 1991, 'Induction of self-tolerance in T cells but not B cells of transgenic mice expressing little self antigen', Science, 251, pp. 1223 - 1225, http://dx.doi.org/10.1126/science.1900950
1991
Hartley SB; Crosbie J; Brink R; Kantor AB; Basten A; Goodnow CC, 1991, 'Elimination from peripheral lymphoid tissues of self-reactive B lymphocytes recognizing membrane-bound antigens', Nature, 353, pp. 765 - 769, http://dx.doi.org/10.1038/353765a0
1991
Adams E; Basten A; Goodnow CC, 1990, 'Intrinsic B-cell hyporesponsiveness accounts for self-tolerance in lysozyme/anti-lysozyme double-transgenic mice', Proceedings of the National Academy of Sciences of the United States of America, vol. 87, pp. 5687 - 5691, http://dx.doi.org/10.1073/pnas.87.15.5687
1990
Goodnow CC; Adelstein S; Basten A, 1990, 'The need for central and peripheral tolerance in the B cell repertoire', Science, 248, pp. 1373 - 1379, http://dx.doi.org/10.1126/science.2356469
1990
Goodnow CC; Basten A, 1989, 'Self-tolerance in B lymphocytes.', Seminars in immunology, vol. 1, pp. 125 - 135
1989
GOODNOW CC; CROSBIE J; ADELSTEIN S; LAVOIE TB; SMITHGILL SJ; MASON DY; JORGENSEN H; BRINK RA; PRITCHARDBRISCOE H; LOUGHNAN M; LOBLAY RH; TRENT RJ; BASTEN A, 1989, 'CLONAL SILENCING OF SELF-REACTIVE LYMPHOCYTES-B IN A TRANSGENIC MOUSE MODEL', COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY, vol. 54, pp. 907 - 920, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1989JX74600035&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
1989
Goodnow CC; Crosbie J; Jorgensen H; Brink RA; Basten A, 1989, 'Induction of self-tolerance in mature peripheral B lymphocytes', Nature, 342, pp. 385 - 391, http://dx.doi.org/10.1038/342385a0
1989
Goodnow CC, 1989, 'Cellular mechanisms of self-tolerance', Current Opinion in Immunology, 2, pp. 226 - 236, http://dx.doi.org/10.1016/0952-7915(89)90192-1
1989
Berg LJ; Fazekas de B; Ivars F; Goodnow CC; Gilfillan S; Garchon HJ; Davis MM, 1988, 'Expression of T-cell receptor alpha-chain genes in transgenic mice', Molecular and Cellular Biology, 8, pp. 5459 - 5469, http://dx.doi.org/10.1128/MCB.8.12.5459
1988
Goodnow CC; Crosbie J; Adelstein S; Lavoie TB; Smith-Gill SJ; Brink RA; Pritchard-Briscoe H; Wotherspoon JS; Loblay RH; Raphael K; Trent RJ; Basten A, 1988, 'Altered immunoglobulin expression and functional silencing of self-reactive B lymphocytes in transgenic mice', Nature, 334, pp. 676 - 682, http://dx.doi.org/10.1038/334676a0
1988
Davis MM; Gascoigne NR; Lindsten T; Goodnow C; Chien Y, 1987, 'Murine T-cell receptor genes.', Advances in experimental medicine and biology, 213, pp. 13 - 17, http://dx.doi.org/10.1007/978-1-4684-5323-2_2
1987
Gascoigne NRJ; Goodnow CC; Dudzik KI; Davis MM, 1987, 'Secretion of a chimeric T-cell receptor-immunoglobulin protein', Proceedings of the National Academy of Sciences of the United States of America, 84, pp. 2936 - 2940, http://dx.doi.org/10.1073/pnas.84.9.2936
1987
Davis MM; Lindsten T; Gascoigne NR; Goodnow C; Chien YH, 1986, 'Paradigm regained: similarities and differences between T cell receptor and immunoglobulin genes.', Biochemical Society Symposia, vol. 51, pp. 205 - 209
1986
Davis MM; Lindsten T; Gascoigne NRJ; Goodnow C; Chien YH, 1986, 'T-cell receptor gene structure and function', Cellular Immunology, 99, pp. 24 - 28, http://dx.doi.org/10.1016/0008-8749(86)90211-X
1986
Gascoigne NRJ; Waters S; Elliott JF; Victor-Kobrin C; Goodnow C; Davis MM; Bona CA, 1986, 'Expression of T cell receptor genes in an antigen-specific hybridoma and radiation-induced variants', Journal of Experimental Medicine, vol. 164, pp. 113 - 130, http://dx.doi.org/10.1084/jem.164.1.113
1986
Walker KZ; Boux HA; Hayden GE; Goodnow CC; Raison RL, 1985, 'A monoclonal antibody with selectivity for human kappa myeloma and lymphoma cells which has potential as a therapeutic agent.', Advances in experimental medicine and biology, vol. 186, pp. 833 - 841, http://dx.doi.org/10.1007/978-1-4613-2463-8_101
1985
Becker DM; Patten P; Chien YH; Yokota T; Eshhar Z; Giedlin M; Gascoigne NRJ; Goodnow C; Wolf R; Arai KI; Davis MM, 1985, 'Variability and repertoire size of T-cell receptor Vα gene segments', Nature, 317, pp. 430 - 434, http://dx.doi.org/10.1038/317430a0
1985
Walker KZ; Hayden GE; Goodnow CC; Boux HA; Adams E; Basten A; Raison RL, 1985, 'Co-expression of an epitope on human free κ-light chains and on a cytoplasmic component in activated T cells', Journal of Immunology, vol. 134, pp. 1059 - 1064
1985
Goodnow CC; Raison RL, 1985, 'Structural analysis of the myeloma-associated membrane antigen KMA', Journal of Immunology, vol. 135, pp. 1276 - 1280
1985
Preprints
add
Voyer TL; Gervais A; Rosain J; Parent A; Cederholm A; Rinchai D; Bizien L; Hancioglu G; Philippot Q; Gueye MS; Luxman MR; Renkilaraj M; Ogishi M; Soudée C; Migaud M; Rozenberg F; Momenilandi M; Riller Q; Imberti L; Delmonte O; Müller G; Keller B; Orrego J; Gallego WA; Rubin T; Emiroglu M; Parvaneh N; Eriksson D; Aranda-Guillen M; Berrios DI; Vong L; Katelaris CH; Mustillo P; Rädler J; Bohlen J; Celik JB; Astudillo C; Winter S; Guichard A; Béziat V; Bustamante J; Pan-Hammarström Q; Zhang Y; Rosen LB; Holland SM; Kenney H; Boztuğ K; Mahlaoui N; Latour S; Abraham R; Lougaris V; Hauck F; Sediva A; Atschekzei F; Poli MC; Slatter MA; Palterer B; Keller MD; Pinzon-Charry A; Sullivan A; Droney L; Suan D; Aladjidi N; Hie M; Lazaro E; Franco J; Keles S; Malphette M; Pasquet M; Maccari ME; Meinhardt A; Ikinciogullari A; Shahrooei M; Celmeli F; Frosk P; Goodnow CC; Gray PE; Belot A; Kuehn HS; Rosenzweig SD; Licciardi F; Servettaz A; Barlogis V; Guenno GL; Herrmann V-M; Kuijpers T; Ducoux G; Sarrot-Reynauld F; Schuetz C; Cunningham-Rundles C; Rieux-Laucat F; Tangye SG; Sobacchi C; Doffinger R; Warnatz K; Grimbacher B; Fieschi C; Berteloot L; Bryant V; Assant ST; Notarangelo LD; Su H; Neven B; Abel L; Zhang Q; Boisson B; Cobat A; Jouanguy E; Kampe O; Bastard P; Roifman C; Landegren N; Anderson MS; Casanova J-L; Puel A, 2023, Impaired thymic AIRE expression underlies autoantibodies against type I IFNs in humans with inborn errors of the alternative NF-kB pathway, , http://dx.doi.org/10.22541/au.167330741.18394805/v1
2023
Masle-Farquhar E; Jackson KJL; Peters T; Al-Eryani G; Singh M; Payne K; Rao G; Apps G; Kingham J; Jara C; Skvortsova K; Swarbrick A; Ma C; Suan D; Uzel G; Chua I; Leiding J; Heiskanen K; Preece K; Kainulainen L; O’Sullivan M; Cooper M; Seppänen MRJ; Mustjoki S; Brothers S; Vogel T; Brink R; Tangye S; Reed J; Goodnow C, 2022, STAT3gain-of-function mutations connect leukemia with autoimmune disease by pathological dysregulation of NKG2DhiCD8 killer T cells, , http://dx.doi.org/10.1101/2022.02.11.480027
2022
Bryant D; Smith L; Rogers-Broadway KR; Karydis L; Woo J; Blunt MD; Forconi F; Stevenson FK; Goodnow C; Russell A; Humberg P; Packham G; Steele AJ; Strefford JC, 2022, Network analysis reveals a major role for 14q32 cluster miRNAs in determining transcriptional differences between IGHV-mutated and unmutated CLL, , http://dx.doi.org/10.1101/2022.04.26.487675
2022
Al-Eryani G; Bartonicek N; Chan C-L; Anderson A; Harvey K; Wu SZ; Roden D; Wang T; Reeves J; Yeung BZ; Masle-Farquhar E; Goodnow CC; Ma C; Phan TG; Lundeberg J; Junankar S; Swarbrick A, 2022, Integration of single-cell RNA and protein data identifies novel clinically-relevant lymphocyte phenotypes in breast cancers, , http://dx.doi.org/10.1101/2022.05.31.494081
2022
Zammit N; Gray P; Siggs O; Yap JY; Russell A; Cultrone D; Warren J; Walters S; Brink R; Zahra D; Burnett D; Gayevskiy V; Minoche A; Ziegler J; Craig M; Wong M; Benitez-Aguirre P; Teo J; Cowley M; Dinger M; Tangye S; Burke C; Phan T; Goodnow C; Grey S, 2022, Environmental and genetic disease modifiers of haploinsufficiency of A20, , http://dx.doi.org/10.1101/2022.03.19.485004
2022
Rouet R; Henry J; Johansen M; Sobti M; Balachandran H; Langley D; Walker G; Lenthall H; Jackson J; Ubiparipovic S; Mazigi O; Schofield P; Burnett D; Brown S; Martinello M; Hudson B; Gilroy N; Post J; Kelleher A; Jäck H-M; Goodnow C; Turville S; Rawlinson W; Bull R; Stewart A; Hansbro P; Christ D, 2022, Broadly neutralizing SARS-CoV-2 antibodies through epitope-based selection from convalescent patients, , http://dx.doi.org/10.1101/2022.10.19.512954
2022
Ho W-HJ; Law AMK; Masle-Farquhar E; Castillo LE; Mawson A; O’Bryan MK; Goodnow CC; Ortega DG; Oakes SR; Ormandy C, 2021, Activation of the viral sensor oligoadenylate synthetase 2 (Oas2) prevents pregnancy-driven mammary cancer metastases, , http://dx.doi.org/10.21203/rs.3.rs-842107/v1
2021
Masle-Farquhar E; Peters T; Jackson KJL; Singh M; Ma C; Suan D; Uzel G; Chua I; Leiding J; Heiskanen K; Preece K; Kainulainen L; O’Sullivan M; Cooper M; Seppänen MRJ; Mustjoki S; Brothers S; Vogel T; Brink R; Tangye S; Reed J; Goodnow C, 2021, Overactive STAT3 drives accumulation of disease-associated CD21lowB cells, , http://dx.doi.org/10.1101/2021.12.20.473595
2021
Masle-Farquhar E; Peters T; Miosge L; Parish I; Weigel C; Oakes C; Reed J; Goodnow C, 2021, Uncontrolled CD21low age-associated and B1 B cell accumulation caused by failure of an EGR2/3 tolerance checkpoint, , http://dx.doi.org/10.1101/2021.07.01.450650
2021
Masle-Farquhar E; Russell A; Li Y; Zhu F; Rui L; Brink R; Goodnow C, 2020, Loss-of-function of Fbxo10, encoding a post-translational regulator of BCL2 in lymphomas, has no discernible effect on BCL2 or B lymphocyte accumulation in mice, , http://dx.doi.org/10.1101/2020.08.05.237545
2020
Kayagaki N; Kornfeld O; Lee B; Stowe I; O'Rourke K; Li Q; Sandoval W; Yan D; Xu M; Ulas G; Payandeh J; Roose-Girma M; Modrusan Z; Reja R; Sagolla M; Webster J; Cho V; Andrews T; Morris L; Miosge L; Goodnow C; Bertram E; Dixit V, 2020, NINJ1 mediates plasma membrane rupture during lytic cell death, , http://dx.doi.org/10.21203/rs.3.rs-62714/v1
2020
Parish I; Stamp LA; Lorenzo AMD; Fowler SM; Sontani Y; Miosge LA; Howard DR; Goodnow CC; Young HM; Furness JB, 2016, A novel mutation in the nucleoporin NUP35 causes murine degenerative colonic smooth muscle myopathy, , http://dx.doi.org/10.1101/036582
2016
Masle-Farquhar E; Peters TJ; Miosge LA; Parish IA; Weigel C; Oakes CC; Reed JH; Goodnow CC, Uncontrolled CD21 <sup>low</sup> Age-Associated and B1 B Cell Accumulation Caused by Failure of an EGR2/3 Tolerance Checkpoint, , http://dx.doi.org/10.2139/ssrn.3885243
Masle-Farquhar E; Peters TJ; Jackson KJL; Singh M; Ma CS; Suan D; Uzel G; Chua I; Leiding JW; Heiskanen K; Preece K; Kainulainen L; O’Sullivan M; Cooper MA; Seppänen MRJ; Mustjoki S; Brothers S; Vogel TP; Brink R; Tangye SG; Reed JH; Goodnow CC, Overactive STAT3 Drives Accumulation of Disease-Associated CD21 <sup>low</sup> B Cells, , http://dx.doi.org/10.2139/ssrn.3996405
Conference Abstracts
add
Allen IA; Russell A; Jackson KJ; Peters T; Gibson G; Joshua AM; Goodnow CC; Burnett DL; Barnet MB, 2022, 'Abstract 665: Correlation between a CTLA-4 single nucleotide polymorphism and high response to anti-PD1/PDL1 immunotherapy in advanced non small cell lung cancer', in Cancer Research, American Association for Cancer Research (AACR), Vol. 82, pp. 665 - 665, http://dx.doi.org/10.1158/1538-7445.am2022-665
2022
Masle-Farquhar E; Payne K; Jackson K; Rao G; Singh M; El-Eryani G; Brink R; Tangye S; Reed J; Goodnow C, 2019, 'The effects of germline STAT3-activating mutations from autoimmunity and lymphoid malignancy on mouse and human T cell development and function', in EUROPEAN JOURNAL OF IMMUNOLOGY, WILEY, PEOPLES R CHINA, Beijing, Vol. 49, pp. 901 - 901, presented at 17th International Congress of Immunology of the International-Union-of-Immunological-Societies (IUIS), PEOPLES R CHINA, Beijing, 19 October 2019 - 23 October 2019, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000490026902546&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2019
Al-Eryani G; Singh M; Wu S; Carswell S; Jackson K; Junankar S; Bartonicek N; Luciani F; Phan T; Smith M; Goodnow CC; Swarbrick A; Roden D, 2019, 'Linking multi-modal single-cell RNA sequencing with targeted long-read sequencing reveals the clonal and transcriptional profile of lymphocytes', in EUROPEAN JOURNAL OF IMMUNOLOGY, WILEY, PEOPLES R CHINA, Beijing, Vol. 49, pp. 1343 - 1343, presented at 17th International Congress of Immunology of the International-Union-of-Immunological-Societies (IUIS), PEOPLES R CHINA, Beijing, 19 October 2019 - 23 October 2019, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000490026904252&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2019
Wang JJ; Reed JH; Colella AD; Russell AJ; Murray-Brown W; Chataway TK; Jackson KJL; Goodnow CC; Gordon TP, 2019, 'Proteomic profiling and clonal tracking of secreted rheumatoid factors in primary Sjogren's syndrome', in EUROPEAN JOURNAL OF IMMUNOLOGY, WILEY, PEOPLES R CHINA, Beijing, Vol. 49, pp. 776 - 777, presented at 17th International Congress of Immunology of the International-Union-of-Immunological-Societies (IUIS), PEOPLES R CHINA, Beijing, 19 October 2019 - 23 October 2019, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000490026902321&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2019
Boast B; Miosge L; Sontani Y; Kuehn HS; Goodnow CC; Rosenzweig SD; Enders A, 2018, 'A MOUSE MODEL FOR HUMAN CVID CAUSED BY A POINT MUTATION IN IKAROS', in INTERNAL MEDICINE JOURNAL, WILEY, Vol. 48, pp. 27 - 27, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000449673000074&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2018
Tri GP; Tangye S; Wong M; Gray P; Batten M; Goodnow C; Burnett L, 2018, 'CLINICAL IMPACT OF WHOLE GENOME SEQUENCING ON THE DIAGNOSIS AND MANAGEMENT OF PATIENTS WITH PRIMARY IMMUNODEFICIENCY DISEASES - THE CLINICAL IMMUNOGENOMICS RESEARCH CONSORTIUM AUSTRALIA (CIRCA) EXPERIENCE', in INTERNAL MEDICINE JOURNAL, WILEY, Vol. 48, pp. 29 - 29, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000449673000079&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2018
Barnet M; Jackson K; Gao B; Nagrial A; Boyer M; Cooper W; Hui R; Linton A; Tattersall M; Russell A; Gibson G; Cebon J; Long G; Menzies A; Scolyer R; Lacaze P; Brink R; Peters T; Cowley M; Gayevskiy V; Thomas D; Pinese M; Blinman P; Kao S; Goodnow C, 2018, 'Exploring the Germ-Line Contribution to Exceptional Response to PD-1/PD-L1 Inhibition in Patients with NSCLC by Whole Genome Sequencing', in JOURNAL OF THORACIC ONCOLOGY, ELSEVIER SCIENCE INC, Vol. 13, pp. S529 - S529, http://dx.doi.org/10.1016/j.jtho.2018.08.726
2018
Jeelall Y; Singh M; Lai J; Ali S; Jackson K; Hollingsworth PN; de Boer B; Wood B; Reed J; Goodnow C; Mclean-Tooke A; Lucas M, 2018, 'OLIGOCLONAL LYMPHOCYTOSIS ASSOCIATED WITH ELEVATED IL6 AND IL10 IN A CASE OF SEVERE CUTANEOUS ADVERSE DRUG REACTION', in INTERNAL MEDICINE JOURNAL, WILEY, Vol. 48, pp. 28 - 29, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000449673000078&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2018
Burnett D; Schofield P; Langley D; Brink R; Christ D; Goodnow CC, 2017, 'Somatic Hypermutation Serves two independent Functions: Antibody Maturation Away From Binding Self and Towards Binding Foreign', in EUROPEAN JOURNAL OF IMMUNOLOGY, WILEY, GERMANY, Erlangen, Vol. 47, pp. 3 - 3, presented at 47th Annual Meeting of the German-Society-for-Immunology (DGFI), GERMANY, Erlangen, 12 September 2017 - 15 September 2017, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000418423100003&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2017
Parnell G; Ong L; Russell A; Swaminathan S; Vucic S; Barnett M; Goodnow C; Booth D; Stewart G, 2017, 'Investigating the shared genetic risk factors for the autoimmune diseases Type 1 Diabetes Mellitus and Multiple Sclerosis', in MULTIPLE SCLEROSIS JOURNAL, SAGE PUBLICATIONS LTD, AUSTRALIA, MS Res Australia, Sydney, Vol. 23, pp. NP20 - NP20, presented at Progress in MS Research Conference, AUSTRALIA, MS Res Australia, Sydney, 11 October 2017 - 13 October 2017, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000414783200055&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2017
Goodnow C; Reed J; Burnett D; Brink R; Christ D; Schofield P; Perotti S; Enders A; Ziegler J; Wainstein B; Roscioli T; Gray P, 2016, 'Redemption or Revolt of Forbidden Clones: Mutations, Autoantibodies and CTLA4-Ig Therapy', in EUROPEAN JOURNAL OF IMMUNOLOGY, WILEY-BLACKWELL, AUSTRALIA, Melbourne, Vol. 46, pp. 3 - 3, presented at International Congress of Immunology (ICI), AUSTRALIA, Melbourne, 21 August 2016 - 26 August 2016, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000383610400007&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2016
Boast B; Reed J; Bergmann H; Yabas M; Roots C; Young C; Nutt S; Goodnow C; Enders A, 2016, 'Deregulation of PAX5 causes abnormal B cell lymphopoiesis and spontaneous precursor B cell lymphoma development in mice', in EUROPEAN JOURNAL OF IMMUNOLOGY, WILEY-BLACKWELL, AUSTRALIA, Melbourne, Vol. 46, pp. 1080 - 1080, presented at International Congress of Immunology (ICI), AUSTRALIA, Melbourne, 21 August 2016 - 26 August 2016, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000383610402567&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2016
Zammit N; Horikawa K; Langley D; Walters S; Goodnow C; Grey S, 2016, 'A20 as a master regulator of islet inflammation and diabetes', in EUROPEAN JOURNAL OF IMMUNOLOGY, WILEY-BLACKWELL, AUSTRALIA, Melbourne, Vol. 46, pp. 319 - 319, presented at International Congress of Immunology (ICI), AUSTRALIA, Melbourne, 21 August 2016 - 26 August 2016, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000383610400642&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2016
Hu DY; Singh M; Yap JY; Wirasinha RC; Howard D; Archer S; Goodnow CC; Daley SR, 2016, 'Tolerance by deletion and regulatory T cell differentiation arise from different TCR repertoires during two waves of thymic selection', in EUROPEAN JOURNAL OF IMMUNOLOGY, WILEY-BLACKWELL, AUSTRALIA, Melbourne, Vol. 46, pp. 337 - 338, presented at International Congress of Immunology (ICI), AUSTRALIA, Melbourne, 21 August 2016 - 26 August 2016, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000383610400679&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2016
Reed J; Jackson J; Christ D; Goodnow C, 2016, 'Actively acquired self-tolerance by clonal redemption of autoantibodies during human immunization', in EUROPEAN JOURNAL OF IMMUNOLOGY, WILEY-BLACKWELL, AUSTRALIA, Melbourne, Vol. 46, pp. 805 - 806, presented at International Congress of Immunology (ICI), AUSTRALIA, Melbourne, 21 August 2016 - 26 August 2016, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000383610402009&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2016
Burnett D; Schofield P; Christ D; Brink R; Goodnow C, 2016, 'Somatic hypermutation serves two independent functions: antibody maturation away from binding self and towards binding foreign', in EUROPEAN JOURNAL OF IMMUNOLOGY, WILEY-BLACKWELL, AUSTRALIA, Melbourne, Vol. 46, pp. 803 - 804, presented at International Congress of Immunology (ICI), AUSTRALIA, Melbourne, 21 August 2016 - 26 August 2016, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000383610402005&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2016
Conference Papers
add
Masle-Farquhar E; Peters T; Oakes C; Reed J; Goodnow CC, 2021, 'EGR2 and EGR3 function in a cell-intrinsic and partially redundant manner to suppress the accumulation of B1a cells and CD21(low) CD23(low) age-associated B cells', in JOURNAL OF IMMUNOLOGY, AMER ASSOC IMMUNOLOGISTS, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000713665800392&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2021
Singh M; Jackson K; Wang JJ; Schofield P; Field M; Peters T; Luciani F; Gordon T; Goodnow C; Reed JH, 2019, '241 Single cell genomics of self-reactive B cells reveals the evolution from benign to pathogenic autoantibody and strategies for early diagnosis and personalised treatment', in Abstracts, Lupus Foundation of America, pp. a178.1 - a1a178, presented at 13th International Congress on Systemic Lupus Erythematosus (LUPUS 2019), San Francisco, California, USA, April 5–8, 2019, Abstract Presentations, http://dx.doi.org/10.1136/lupus-2019-lsm.241
2019
Barnet M; Pathmanandavel S; McCarthy L; Goodnow C; Joshua A, 2019, 'The Australian Exceptional Responders Program: A national collaboration', in ANNALS OF ONCOLOGY, OXFORD UNIV PRESS, SPAIN, Barcelona, presented at 44th Congress of the European-Society-for-Medical-Oncology (ESMO), SPAIN, Barcelona, 27 September 2019 - 01 October 2019, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000491295505242&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2019
Barnet MB; Jackson KJ; Gao B; Nagrial AM; Boyer MJ; Cooper WA; Hui R; Linton A; Tattersall MH; Gibson G; Cebon J; Long GV; Menzies AM; Scolyer RA; Lacaze P; Brink R; Peters T; Cowley M; Gayevskiy V; Thomas DM; Pinese M; Blinman P; Kao S; Goodnow CC, 2018, 'Exploring the germ-line contribution to exceptional response to PD-1/PD-L1 inhibition in patients with metastatic non-small-cell lung cancer by whole genome sequencing', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, IL, Chicago, presented at Annual Meeting of the American-Association-for-Cancer-Research (AACR), IL, Chicago, 14 April 2018 - 18 April 2018, http://dx.doi.org/10.1158/1538-7445.AM2018-LB-121
2018
Coombes C; Tobin JWD; Saxena K; Lim JH; Shadbolt B; Jeelall Y; Goodnow C; Thomas AD; Jain S; Jiang S; Horikawa K; Talaulikar D, 2017, 'Mutation Analysis and Effect on Prognosis of Direct Antiglobulin Test Positivity in Diffuse Large B-Cell Lymphoma', in BLOOD, AMER SOC HEMATOLOGY, GA, Atlanta, presented at 59th Annual Meeting of the American-Society-of-Hematology (ASH), GA, Atlanta, 09 December 2017 - 12 December 2017, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000432419705316&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2017
Koay H-F; Rahimpour A; Enders A; Clanchy R; Eckle S; Meehan B; Chen Z; Whittle B; Liu L; Fairlie D; Goodnow C; McCluskey J; Rossjohn J; Uldrich A; Pellicci D; Godfrey D, 2016, 'Identification of phenotypically and functionally heterogeneous mouse Mucosal Associated Invariant T cells using MR1 tetramers', in EUROPEAN JOURNAL OF IMMUNOLOGY, WILEY-BLACKWELL, AUSTRALIA, Melbourne, pp. 254 - 254, presented at International Congress of Immunology (ICI), AUSTRALIA, Melbourne, 21 August 2016 - 26 August 2016, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000383610400513&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2016
Godfrey D; Koay H-F; Gherardin N; Enders A; Loh L; Chen Z; Corbett A; Eckle S; Meehan B; d'Udekem Y; Konstantinov I; Lappas M; Liu L; Goodnow C; Fairlie D; Rossjohn J; Kedzierska K; Berzins S; McCluskey J; Uldrich A; Pellicci D, 2016, 'Thymic precursors to the mucosal-associated invariant T cell lineage', in EUROPEAN JOURNAL OF IMMUNOLOGY, WILEY-BLACKWELL, AUSTRALIA, Melbourne, pp. 256 - 257, presented at International Congress of Immunology (ICI), AUSTRALIA, Melbourne, 21 August 2016 - 26 August 2016, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000383610400518&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2016
Jeelall Y; Ziolkowski A; Andrews D; Field M; Jain S; Goodnow C; Cook M; Talaulikar D, 2015, 'A NOVEL ULTRA-DEEP SEQUENCING METHOD FOR TRACKING OF DRIVER MUTATIONS IDENTIFIES THE MYD88 L265P MUTATION IN EARLY HAEMOPOIETIC PRECURSORS IN DIFFUSE LARGE B CELL LYMPHOMA', in HAEMATOLOGICA, FERRATA STORTI FOUNDATION, AUSTRIA, Vienna, pp. 106 - 106, presented at 20th Congress of European-Hematology-Association, AUSTRIA, Vienna, 11 June 2015 - 14 June 2015, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000361204901224&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2015
Jiang S; Athanasopoulos V; Capello J; Walters G; Ellyard J; Alexander SI; Kitching R; Weber A; Field M; Andrews D; Pascual V; Goodnow C; Cook M; Vinuesa C, 2015, 'BANK1: A CRITICAL GENETIC DETERMINANT OF B-CELL SYSTEMIC LUPUS ERYTHEMATOSUS', in NEPHROLOGY, WILEY-BLACKWELL, pp. 22 - 22, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000360217000021&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2015
Enders A; Short A; Miosge LA; Bergmann H; Lambe SJ; Sontani Y; Yabas M; Bertram EM; Whittle B; Balakishnan B; Yoshida K; Field MA; Andrews TD; Hagiwara H; Goodnow CC, 2014, 'Expression of IgD on Mature Lymphocytes Is Dependent on Zinc-Finger Protein ZFP318', in JOURNAL OF CLINICAL IMMUNOLOGY, SPRINGER/PLENUM PUBLISHERS, CZECH REPUBLIC, Prague, pp. S429 - S429, presented at 16th Biennial Meeting of the European-Society-for-Immunodeficiencies, CZECH REPUBLIC, Prague, 29 October 2014 - 01 November 2014, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000347389100626&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2014
Zammit N; Walters S; Jeanette V; Malle E; Goodnow C; Grey S, 2014, 'The OTU Domain of A20 Silences the Tissue Microenvironment for Immunological Non-Responsiveness.', in AMERICAN JOURNAL OF TRANSPLANTATION, WILEY-BLACKWELL, CA, San Francisco, pp. 684 - 684, presented at World Transplant Congress, CA, San Francisco, 26 July 2014 - 31 July 2014, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000338033303092&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2014
Talaulikar D; Jeelall Y; Ziolkowski A; Cook M; Jain S; Andrews D; Field M; Goodnow C, 2014, 'Genetics of Disease Progression in Diffuse Large B-Cell Lymphoma: Clonal Selection and Acquisition of Newly Acquired Somatic Mutations at Relapse', in BLOOD, AMER SOC HEMATOLOGY, CA, San Francisco, presented at 56th Annual Meeting of the American-Society-of-Hematology, CA, San Francisco, 06 December 2014 - 09 December 2014, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000349233806216&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2014
Fuchs S; Rensing-Ehl A; Pannicke U; Lorenz M; Jeelall Y; Rohr J; Speckmann C; Vraetz T; Farmand S; Schmitt-Graeff A; Fisch P; Strahm B; Henneke P; Enders A; Horikawa K; Goodnow C; Schwarz K; Ehl S, 2014, 'Omenn Syndrome Associated with a Functional Reversion Due to a Somatic Second-Site Mutation in CARD11 Deficiency', in JOURNAL OF CLINICAL IMMUNOLOGY, SPRINGER/PLENUM PUBLISHERS, CZECH REPUBLIC, Prague, pp. S474 - S475, presented at 16th Biennial Meeting of the European-Society-for-Immunodeficiencies, CZECH REPUBLIC, Prague, 29 October 2014 - 01 November 2014, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000347389100725&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2014
Zammit N; Walters S; Jeanette V; Malle E; Goodnow C; Grey S, 2014, 'The OTU Domain of A20 Silences the Tissue Microenvironment for Immunological Non-Responsiveness.', in TRANSPLANTATION, LIPPINCOTT WILLIAMS & WILKINS, CA, San Francisco, pp. 684 - 684, presented at World Transplant Congress, CA, San Francisco, 26 July 2014 - 31 July 2014, http://dx.doi.org/10.1097/00007890-201407151-02326
2014
Hillen K; Gather R; Enders A; Pircher H; Aichele P; Fisch P; Blumenthal B; Schamel W; Straub T; Goodnow C; Ehl S, 2014, 'T Cell Proliferation Rather than T Cell Effector Function Is the Limiting Factor of Antiviral Immunity in Mice with a Partial Defect in TCR Signaling', in JOURNAL OF CLINICAL IMMUNOLOGY, SPRINGER/PLENUM PUBLISHERS, CZECH REPUBLIC, Prague, pp. S444 - S444, presented at 16th Biennial Meeting of the European-Society-for-Immunodeficiencies, CZECH REPUBLIC, Prague, 29 October 2014 - 01 November 2014, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000347389100657&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2014
Randall KL; Law HD; Goodnow CC; Daley SR, 2014, 'Investigation of T-REG cells in DOCK8 immunodeficiency', in ALLERGY, WILEY-BLACKWELL, DENMARK, Copenhagen, pp. 495 - 495, presented at European-Academy-of-Allergy-and-Clinical-Immunology Congress, DENMARK, Copenhagen, 07 June 2014 - 11 June 2014, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000341139401477&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2014
Randall KL; Law H-D; Goodnow CC, 2013, 'T CELL SUBSETS IN A MOUSE MODEL OF AUTOSOMAL RECESSIVE HYPER-IgE SYNDROME', in INTERNAL MEDICINE JOURNAL, WILEY-BLACKWELL, pp. 15 - 15, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000323685200048&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2013
Randall KL; Sabouri Z; Goodnow CC, 2012, 'MEMORY B CELLS IN DOCK8 DEFICIENT MICE', in JOURNAL OF CLINICAL IMMUNOLOGY, SPRINGER/PLENUM PUBLISHERS, ITALY, Florence, pp. 253 - 253, presented at 15th Biennial Meeting European-Society-for-Immunodeficiency (ESID), ITALY, Florence, 03 October 2012 - 06 October 2012, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000308728900517&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2012
Bergmann H; Yabas M; Short A; Miosge L; Barthel N; Teh CE; Roots CM; Bull K; Jeelall Y; Horikawa K; Whittle B; Balakishnan B; Sjollema G; Bertram EM; Mackay F; Rimmer A; Cornall R; Field MA; Andrews DT; Goodnow CC; Enders A, 2012, 'MUTATIONS IN THE INTRAMEMBRANE ENDOPEPTIDASE SPPL2A AFFECT HUMORAL IMMUNITY AND B-CELL SURVIVAL BY REDUCING SURFACE BCR AND BAFF-R EXPRESSION AND AFFECTING CD74 METABOLISM', in JOURNAL OF CLINICAL IMMUNOLOGY, SPRINGER/PLENUM PUBLISHERS, ITALY, Florence, pp. 11 - 12, presented at 15th Biennial Meeting European-Society-for-Immunodeficiency (ESID), ITALY, Florence, 03 October 2012 - 06 October 2012, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000308728900019&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2012
Coakley K; Daley S; Hu D; Randall K; Jenne C; Limnander A; Goodnow C; Roose J, 2012, 'An Autoimmune Mutation in Rasgrp1 Reveals Unique Compensation in Thymocyte Selection', in DIGESTIVE DISEASES AND SCIENCES, SPRINGER, pp. 2729 - 2729, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000309867800008&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2012
Yabas M; Teh CE; Frankenreiter S; Lal D; Whittle B; Andrews DT; Kucharska EM; Broer S; Goodnow CC; Enders A, 2012, 'Flipping of lipids by a putative transporter is essential for B-cell development and function', in IMMUNOLOGY, WILEY-BLACKWELL, SCOTLAND, Glasgow, pp. 365 - 365, presented at European Congress of Immunology, SCOTLAND, Glasgow, 05 September 2012 - 08 September 2012, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000309189102261&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2012
Drini M; Yabas M; Enders A; Goodnow CC; Farrell GC; Teoh NC, 2011, 'Intrahepatic cholestasis in ATP11c (phosphotidylserine transferase) mutant mice is associated with apoptosis and hepatocarcinogenesis', in JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, WILEY-BLACKWELL, pp. 10 - 11, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000295157300027&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2011
Altin J; Goodnow C; Cook M, 2011, 'IL-10 production by Th2 cells in vivo occurs by sub-differentiation into a novel, suppressive IL-10+CTLA-4hi Th2 subset', in JOURNAL OF IMMUNOLOGY, AMER ASSOC IMMUNOLOGISTS, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000209751706069&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2011
Randall K; Lambe T; Johnson A; Kucharska E; Vinuesa C; Treanor B; Batista F; Chan T; Camidge T; Brink R; Cornall R; Goodnow C, 2010, 'Immunodeficiency and Abnormal B Cell Synapse Formation due to DOCK8 Mutations in Mice', in CLINICAL IMMUNOLOGY, ACADEMIC PRESS INC ELSEVIER SCIENCE, MA, Boston, pp. S17 - S17, presented at 10th Annual Meeting of the Federation-of-Clinical-Immunology-Societies, MA, Boston, 24 June 2010 - 27 June 2010, http://dx.doi.org/10.1016/j.clim.2010.03.055
2010
Zikherman J; Watson S; Jenne C; Raschke WC; Goodnow C; Weiss A, 2009, 'An allelic series of CD45 dosages uncouples basal and inducible TCR signaling during thymic development', in JOURNAL OF IMMUNOLOGY, AMER ASSOC IMMUNOLOGISTS, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000209763601236&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2009
Goodnow CC; Campbell JA; Rui L; Vinuesa CG, 2007, 'Tolerance mechanisms in the late phase of the antibody response', in Advances in Experimental Medicine and Biology, pp. 163 - 168, http://dx.doi.org/10.1007/0-387-46530-8_15
2007
Socha L; Goodnow CC; Nolan CJ, 2007, 'Synthesis of disulfide-bonded proteins causes non-immune beta-cell damage in a transgenic substrain of non-obese diabetic (NOD) mice', in DIABETES, AMER DIABETES ASSOC, IL, Chicago, pp. A412 - A412, presented at 67th Annual Meeting of the American-Diabetes-Association, IL, Chicago, 22 June 2007 - 26 June 2007, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000246930202518&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2007
Perkins AC; Tallack M; Zhan Y; Papathanasiou P; Goodnow C; Gaensler K; Crossley PM; Dekker J; Keys JR, 2007, 'Ikaros drives human haemoglobin switching by facilitating active chromatin hub formation', in BLOOD, AMER SOC HEMATOLOGY, GA, Atlanta, pp. 526A - 526A, presented at 49th Annual Meeting of the American-Society-of-Hematology, GA, Atlanta, 08 December 2007 - 11 December 2007, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000251100802294&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2007
Eri RD; Florin TH; Price G; Heazlewood CK; Cook MC; Goodnow CC; Mcguckin MA, 2007, 'Endoplasmic reticulum stress in goblet cells leads directly to intestinal inflammation with similarities to ulcerative colitis', in GASTROENTEROLOGY, W B SAUNDERS CO-ELSEVIER INC, DC, Washington, pp. A8 - A8, presented at Digestive Disease Weeking Meeting/ASGE Postgraduate Course Meeting, DC, Washington, 19 May 2007 - 24 May 2007, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000245927600034&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2007
Mcguckin MA; Eri R; Heazlewood CK; Cook MC; Taupin DR; Thornton DJ; Png CW; Crockford TL; Cornall RJ; Kato M; Nelms KA; Hong NA; Goodnow CC; Florin TH, 2007, 'Aberrant mucin assembly links endoplasmic reticulum stress with ulcerative colitis', in GASTROENTEROLOGY, W B SAUNDERS CO-ELSEVIER INC, DC, Washington, pp. A388 - A388, presented at Digestive Disease Weeking Meeting/ASGE Postgraduate Course Meeting, DC, Washington, 19 May 2007 - 24 May 2007, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000245927603203&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2007
Alexander WS; Belz G; Britton WJ; Cook M; Cyster J; Goodnow CC; Hume D; Kaufman J; Mackay C; Stacker S; Turner S, 2007, 'Discussion', in Novartis Foundation Symposium, pp. 44 - 49
2007
Britton WJ; Casanova JL; Foote S; Goodnow CC; Gros P; Hume D; Karupiah G; Mackay C; Morahan G; Turner S; Young D, 2007, 'Discussion', in Novartis Foundation Symposium, pp. 177 - 180
2007
Foote S; Fortin A; Goodnow CC; Gros P; Morahan G; Vinuesa C; Wakeland EK, 2007, 'Discussion', in Novartis Foundation Symposium, pp. 153 - 155
2007
Wu Z; Goodnow C; Hoyne G, 2007, 'T cell deficiency resulting form aberrant pre-mRNA alternative splicing', in CYTOKINE, ACADEMIC PRESS LTD ELSEVIER SCIENCE LTD, CA, San Francisco, pp. 46 - 46, presented at 15th Annual Meeting of the International-Cytokine-Society, CA, San Francisco, 26 October 2007 - 30 October 2007, http://dx.doi.org/10.1016/j.cyto.2007.07.171
2007
Casanova JL; Britton WJ; Gros P; Morahan G; Hume D; Cyster J; Goodnow CC; Turner S; Cook M, 2007, 'Discussion', in Novartis Foundation Symposium, pp. 89 - 92
2007
Belz G; Britton WJ; Casanova JL; Foote S; Goodnow CC; Gros P; Hume D; Maizels RM; Turner S, 2007, 'Discussion', in Novartis Foundation Symposium, pp. 165 - 168
2007
Keys JR; Papathanasiou P; Goodnow CC; Perkins AC, 2006, 'The transcriptional factor, IKAROS, plays a key role in gamma-beta globin gene switching', in BLOOD CELLS MOLECULES AND DISEASES, ACADEMIC PRESS INC ELSEVIER SCIENCE, ENGLAND, St Johns Coll, Oxford, pp. 168 - 169, presented at 15th Conference on Hemoglobin Switching, ENGLAND, St Johns Coll, Oxford, 14 September 2006 - 18 September 2006, http://dx.doi.org/10.1016/j.bcmd.2006.10.112
2006
Read S; Porter D; O'Bryan M; Goodnow C, 2006, 'NHMRC Australian Phenome Bank', in TRANSGENIC RESEARCH, SPRINGER, pp. 780 - 781, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000242336100023&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2006
Jackson DE; Hayball JD; Goodnow CC; Hogarth MP; Wong MX, 2005, 'PECAM-1-mediated signalling is important in regulation of tolerance and autoimmunity', in TISSUE ANTIGENS, WILEY-BLACKWELL PUBLISHING, INC, AUSTRALIA, Melbourne, pp. 452 - 452, presented at 35th Annual Scientific Meeting of the Australasian-Society-for-Immunology/14th International HLA and Immunogenetics Workshops, AUSTRALIA, Melbourne, 29 November 2005 - 02 December 2005, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000233542700300&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2005
Ting J; Behrens TW; Wakeland EK; Abbas AK; Goodnow CC; Hafler DA; Kuchroo VK; Rioux JD; Wicker LS; Worthington J; Vyse TJ; Goldstein DB; Foote SJ; Kere J, 2005, 'Discussion', in Novartis Foundation Symposium, pp. 160 - 164
2005
Makaroff LE; Goodnow CC; Fahrer AM, 2005, 'The essential role of condensin II for normal T lymphocyte development', in TISSUE ANTIGENS, BLACKWELL PUBLISHING, AUSTRALIA, Melbourne, pp. 485 - 486, presented at 35th Annual SCientific Meeting of the Australasian-Society-for-Immunology/14th International HLA and Immunogenetics Workshops, AUSTRALIA, Melbourne, 29 November 2005 - 02 December 2005, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000233542700391&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2005
Silva DG; Goodnow CC; Vinuesa CG, 2005, 'The ubiquitin ligase (Roquin) maintains peripheral T cell tolerance and represses autoimmune diabetes', in TISSUE ANTIGENS, BLACKWELL PUBLISHING, AUSTRALIA, Melbourne, pp. 542 - 542, presented at 35th Annual SCientific Meeting of the Australasian-Society-for-Immunology/14th International HLA and Immunogenetics Workshops, AUSTRALIA, Melbourne, 29 November 2005 - 02 December 2005, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000233542700546&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2005
Abbas AK; Cookson W; Foote SJ; Goldstein DB; Goodnow CC; Hafler DA; Kere J; Kuchroo VK; Rao A; Seed B; Lineberger JT; Umetsu D, 2005, 'Discussion', in Novartis Foundation Symposium, pp. 52 - 56
2005
Gosling KM; Goodnow CC; Fahrer AM, 2005, 'Condensin II, the chromosome compactor, influences T cell-dependent antibody responses', in TISSUE ANTIGENS, BLACKWELL PUBLISHING, AUSTRALIA, Melbourne, pp. 431 - 431, presented at 35th Annual SCientific Meeting of the Australasian-Society-for-Immunology/14th International HLA and Immunogenetics Workshops, AUSTRALIA, Melbourne, 29 November 2005 - 02 December 2005, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000233542700244&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2005
Liston A; Goodnow CC, 2005, 'Genetic lesions in thymic T cell clonal deletion and thresholds for autoimmunity', in Novartis Foundation Symposium, pp. 180 - 192
2005
Cook M; Vinuesa C; Nelms K; Goodnow C, 2005, 'ENU mutagenesis based screens', in INFLAMMATION RESEARCH, SPRINGER BASEL AG, pp. S85 - S85, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000205501600003&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2005
Abbas AK; Wijmenga C; Rioux JD; Seed B; Cookson W; Goodnow CC; Bowcock A; Umetsu D; Hafler DA; Kuchroo VK; Wakeland EK; Lindgren C; Ting J; Wicker LS; Vyse TJ, 2005, 'Discussion', in Novartis Foundation Symposium, pp. 134 - 144
2005
Hafler DA; Rao A; Ting J; Rioux JD; Goodnow CC; Abbas AK; Wicker LS; Wakeland EK; Behrens TW; Goldstein DB; Kere J; Cookson W; Seed B; Lindgren C; Bowcock A; Kuchroo VK, 2005, 'Discussion', in Novartis Foundation Symposium, pp. 174 - 179
2005
Hafler DA; Rao A; Goodnow CC; Abbas AK; Wakeland EK; Behrens TW; Goldstein DB; Kere J; Cookson W; Seed B; Lindgren C; Bowcock A; Kuchroo VK; Vyse TJ; Wijmenga C; Wicker LS, 2005, 'Discussion', in Novartis Foundation Symposium, pp. 192 - 199
2005
Vinuesa CG; Yu D; Athanasopoulos V; Silva D; Linterman M; Hill KM; Goodnow CC, 2005, 'Stress granules maintain T and B cell cell tolerance', in TISSUE ANTIGENS, BLACKWELL PUBLISHING, AUSTRALIA, Melbourne, pp. 579 - 579, presented at 35th Annual SCientific Meeting of the Australasian-Society-for-Immunology/14th International HLA and Immunogenetics Workshops, AUSTRALIA, Melbourne, 29 November 2005 - 02 December 2005, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000233542700646&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2005
Bertram EM; Read SH; O'Bryan MK; DeKretzer DM; Goodnow CC, 2005, 'Unlocking the mammalian "phenome double right arrow genome" code with the support of the Australian Phenomics Facility', in TISSUE ANTIGENS, WILEY-BLACKWELL PUBLISHING, INC, AUSTRALIA, Melbourne, pp. 361 - 361, presented at 35th Annual Scientific Meeting of the Australasian-Society-for-Immunology/14th International HLA and Immunogenetics Workshops, AUSTRALIA, Melbourne, 29 November 2005 - 02 December 2005, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000233542700053&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2005
Bertram EM; Yates AL; Linares D; Sheahan DJ; Young N; Subramaniam AS; Whittle B; Johnson A; Fordham SA; Murtagh A; Kucharska EM; Domashenz H; Willenborg DO; Vinuesa CG; Goodnow CC, 2005, 'Molecular and cellular analysis of the ENU-induced mouse gene variant, face, with a point mutation in STAT-1 responsible for spontaneous T cell hyperactivity', in TISSUE ANTIGENS, WILEY-BLACKWELL PUBLISHING, INC, AUSTRALIA, Melbourne, pp. 361 - 361, presented at 35th Annual Scientific Meeting of the Australasian-Society-for-Immunology/14th International HLA and Immunogenetics Workshops, AUSTRALIA, Melbourne, 29 November 2005 - 02 December 2005, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000233542700054&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2005
Siggs OM; Miosge LA; Goodnow CC; Liston A, 2005, 'Intermediate genetic lesions in TCR signal transduction induce spontaneous autoimmunity and immune deysregulation', in TISSUE ANTIGENS, BLACKWELL PUBLISHING, AUSTRALIA, Melbourne, pp. 542 - 542, presented at 35th Annual SCientific Meeting of the Australasian-Society-for-Immunology/14th International HLA and Immunogenetics Workshops, AUSTRALIA, Melbourne, 29 November 2005 - 02 December 2005, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000233542700545&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2005
Goldstein DB; Abbas AK; Wijmenga C; Cookson W; Goodnow CC; Rioux JD; Hafler DA; Kere J; Daly MJ; Bowcock A; Behrens TW; Foote SJ; Worthington J, 2005, 'Discussion', in Novartis Foundation Symposium, pp. 8 - 13
2005
Goldstein DB; Foote SJ; Hafler DA; Daly MJ; Kere J; Abbas AK; Goodnow CC; Seed B; Rioux JD; Wakeland EK; Cookson W, 2005, 'Discussion', in Novartis Foundation Symposium, pp. 39 - 45
2005
Daly MJ; Goldstein DB; Rioux JD; Hafler DA; Seed B; Bowcock A; Kere J; Foote SJ; Cookson W; Wakeland EK; Goodnow CC; Abbas AK; Rao A; Ting J; Vyse TJ; Wicker LS, 2005, 'Discussion', in Novartis Foundation Symposium, pp. 19 - 30
2005
Perkins AC; Papathanasiou P; Goodnow CC; Keys JR, 2005, 'Specific activation of human beta-globin gene expression by the transcription factor Ikaros', in BLOOD, AMER SOC HEMATOLOGY, GA, Atlanta, pp. 1013A - 1014A, presented at 47th Annual Meeting of the American-Society-of-Hematology, GA, Atlanta, 10 December 2005 - 13 December 2005, http://dx.doi.org/10.1182/blood.V106.11.3641.3641
2005
Fahrer AM; Gosling KM; Makaroff L; Theodoratos A; Goodnow CC, 2005, 'A surprising T cell specific requirement for chromosome condensin II', in TISSUE ANTIGENS, BLACKWELL PUBLISHING, AUSTRALIA, Melbourne, pp. 409 - 409, presented at 35th Annual SCientific Meeting of the Australasian-Society-for-Immunology/14th International HLA and Immunogenetics Workshops, AUSTRALIA, Melbourne, 29 November 2005 - 02 December 2005, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000233542700186&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2005
Liston A; Siggs OM; Goodnow CC, 2005, 'Genetic lesions leading to defective T cell tolerance and autoimmunity', in TISSUE ANTIGENS, BLACKWELL PUBLISHING, AUSTRALIA, Melbourne, pp. 481 - 481, presented at 35th Annual SCientific Meeting of the Australasian-Society-for-Immunology/14th International HLA and Immunogenetics Workshops, AUSTRALIA, Melbourne, 29 November 2005 - 02 December 2005, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000233542700377&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2005
Kennedy CL; O'Connor AE; Sanchez-Partida LG; Goodnow CC; de Kretser DM; O'Bryan MK, 2004, 'The development of forward and reverse genetics approaches to identify key male fertility related genes using ENU mutagenesis', in JOURNAL OF ANDROLOGY, AMER SOC ANDROLOGY, INC, MD, Baltimore, pp. 69 - 69, presented at 29th Annual Meeting of the American-Society-of-Andrology (ASA 2004), MD, Baltimore, 17 April 2004 - 20 April 2004, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000220231800094&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2004
Socha L; Silva D; Lesage S; Goodnow C; Petrovsky N, 2003, 'The role of endoplasmic reticulum stress in nonimmune diabetes: NOD.k iHEL, a novel model of β cell death', in Annals of the New York Academy of Sciences, pp. 178 - 183, http://dx.doi.org/10.1196/annals.1288.022
2003
Goodnow CC; Jun J; Lesage S; Loy A; Miosge L; Papathanasiou P; Fahrer A; Martin S; Rui LX; de Vinuesa CG; Glynne R; Nelms K; Hong N, 2003, 'Tolerogenic versus immunogenic signalling', in FASEB JOURNAL, FEDERATION AMER SOC EXP BIOL, COLORADO, DENVER, pp. C260 - C260, presented at 90th Annual Meeting of the American-Association-for-Immunologists, COLORADO, DENVER, 06 May 2003 - 10 May 2003, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000182367001213&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2003
Vinuesa CG; Cook MC; Cooke MP; MacLennan ICM; Goodnow CC, 2002, 'Analysis of B cell memory formation using DNA microarrays', in Annals of the New York Academy of Sciences, pp. 33 - 45, http://dx.doi.org/10.1111/j.1749-6632.2002.tb05939.x
2002
Goodnow C; Chaudhry S; Miosge L; Papathanasiou P; Yates A; Jun J; Wilson L; Hardy J; Nelms K, 2002, 'Elucidating molecular pathways in human health by genome-wide mutagenesis in mice', in CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY, BLACKWELL PUBLISHING ASIA, AUSTRALIA, MELBOURNE, pp. A55 - A55, presented at 24th Annual Scientific Meeting of High-Blood-Pressure-Research-Council-of-Australia-Inc, AUSTRALIA, MELBOURNE, 25 November 2002 - 29 November 2002, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000184207100079&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2002
Goodnow CC; Glynne R; Mack D; Weintraub B; Rathmell J; Healy JI; Chaudhry S; Miosge L; Loy A; Wilson L, 1999, 'Mechanisms of self-tolerance and autoimmunity: From whole-animal phenotypes to molecular pathways', in Cold Spring Harbor Symposia on Quantitative Biology, pp. 313 - 322, http://dx.doi.org/10.1101/sqb.1999.64.313
1999
Prodeus AP; Goerg S; Shen LM; Pozdnyakova OO; Alicot EM; Goodnow CC; Carroll MC, 1998, 'A critical role of complement in regulation of self-reactive B cells.', in MOLECULAR IMMUNOLOGY, PERGAMON-ELSEVIER SCIENCE LTD, pp. 338 - 338, http://dx.doi.org/10.1016/S0161-5890(98)90562-4
1998
Goodnow CC, 1997, 'Balancing immunity, autoimmunity, and self-tolerance', in Annals of the New York Academy of Sciences, pp. 55 - 60, http://dx.doi.org/10.1111/j.1749-6632.1997.tb52044.x
1997
Inaoki M; Sato S; Goodnow CC; Tedder TF, 1997, 'CD19 regulates peripheral tolerance in B lymphocytes.', in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, MOSBY-YEAR BOOK INC, pp. 1521 - 1521, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1997WH14201520&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
1997
Fang W; Weintraub B; Goodnow C; Jenkins M; Mueller D; Behrens T, 1997, 'Self-reactive B cells that escape negative selection are rendered anergic in the periphery', in ARTHRITIS AND RHEUMATISM, LIPPINCOTT-RAVEN PUBL, pp. 465 - 465, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1997XY63400464&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
1997
Goodnow CC, 1996, 'Balancing immunity, autoimmunity and self tolerance in B lymphocytes', in Banchereau J; Dodet B; Schwartz R; Trannoy E (eds.), IMMUNE TOLERANCE, EDITIONS SCIENTIFIQUE & MEDICALES ELSEVIER, FRANCE, ANNECY, pp. 73 - 83, presented at International Symposium on Immune Tolerance, FRANCE, ANNECY, 09 May 1996 - 11 May 1996, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1996BH33J00007&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
1996
ESSER U; HO WY; COOKE MP; GOODNOW CC; DAVIS MM, 1995, 'ELIMINATION OF ANERGIC B-CELLS BY ANTIGEN-SPECIFIC T-CELLS AND SURVIVAL IN THE PRESENCE OF THE BCL-2 TRANSGENE', in JOURNAL OF CELLULAR BIOCHEMISTRY, WILEY-LISS, pp. 93 - 93, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1995QT86400319&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
1995
White GC; Briet E; Gilles JGG; Hoyer LW; Kazatchkine M; Montgomery RR; Preston FE; Reisner HM; Aledort LM; Aronson D; Goodnow C; Jenkins M; Kay M; Monroe DM; Scandella D; Scott DW, 1995, 'Panel discussion on the development of inhibitors: Who and why?', in Advances in Experimental Medicine and Biology, pp. 235 - 246
1995
HEALY JI; MCMAHON M; COOKE MP; MACK D; DAVIS MM; GOODNOW CC, 1995, 'DIVERGING SIGNALS CONTROL PROLIFERATION AND DIFFERENTIATION OF SELF-REACTIVE B-LYMPHOCYTES', in JOURNAL OF CELLULAR BIOCHEMISTRY, WILEY-LISS, pp. 72 - 72, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1995QT86400238&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
1995
COOKE MP; HEATH AW; SHOKAT KM; ZENG YJ; HOWARD M; GOODNOW CC, 1994, 'IMMUNOGLOBULIN SIGNAL-TRANSDUCTION GUIDES B-CELL T-CELL INTERACTIONS AND IS BLOCKED IN TOLERANT SELF-REACTIVE B-CELLS', in JOURNAL OF CELLULAR BIOCHEMISTRY, WILEY-LISS, pp. 397 - 397, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1994NE25401345&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
1994
HARTLEY SB; GOODNOW CC, 1994, 'CENSORING OF SELF-REACTIVE B-CELLS WITH A RANGE OF RECEPTOR AFFINITIES IN TRANSGENIC MICE EXPRESSING HEAVY-CHAINS FOR A LYSOZYME-SPECIFIC ANTIBODY', in JOURNAL OF CELLULAR BIOCHEMISTRY, WILEY-LISS, pp. 386 - 386, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1994NE25401304&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
1994
HEATH AW; WU WW; CYSTER JG; GOODNOW CC; HOWARD M, 1994, 'CD40 AND MURINE B-CELL ONTOGENY', in JOURNAL OF CELLULAR BIOCHEMISTRY, WILEY-LISS, pp. 373 - 373, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1994NE25401255&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
1994
POGUE SL; GOODNOW CC, 1994, 'ASSOCIATION OF IGG1 ANTIGEN RECEPTOR WITH 3 NOVEL PHOSPHOPROTEINS IS MEDIATED BY THE HEAVY-CHAIN CYTOPLASMIC DOMAIN', in JOURNAL OF CELLULAR BIOCHEMISTRY, WILEY-LISS, pp. 345 - 345, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1994NE25401143&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
1994
AKKARAJU S; CANAAN K; HO B; GOODNOW C, 1994, 'TOLERANCE AND AUTOIMMUNITY IN THYROID-HEL TRANSGENIC MICE', in JOURNAL OF CELLULAR BIOCHEMISTRY, WILEY-LISS, pp. 313 - 313, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1994NE25401017&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
1994
LUND FE; COOKE M; SANTOSARGUMEDO L; HEATH A; YU N; SOLVASON N; GRIMALDI JC; PARKHOUSE M; GOODNOW C; HOWARD M, 1994, 'CD38 IS FUNCTIONALLY ASSOCIATED WITH THE IG RECEPTOR COMPLEX AND EXHIBITS A SIGNALING DEFECT IN 2 IMMUNODEFICIENT B-CELL SUBSETS', in JOURNAL OF CELLULAR BIOCHEMISTRY, WILEY-LISS, pp. 299 - 299, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1994NE25400979&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
1994
LENSCHOW DJ; FREEMAN G; HODES R; COOKE M; ZENG Y; HATHCOCK K; GRAY G; THISTLETHWAITE JR; GOODNOW C; NADLER LM; BLUESTONE JA, 1994, 'B7-2, AND NOT B7-1(B7), IS THE PRIMARY COSTIMULATORY MOLECULE FOR T-CELL ACTIVATION', in JOURNAL OF CELLULAR BIOCHEMISTRY, WILEY-LISS, pp. 431 - 431, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1994NE25401479&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
1994
GOODNOW CC; AKKARAJU S; BELL SE; CANAAN K; COOKE MP; CYSTER JG; HARTLEY SB; LEONG D; SHOKAT KM; RATHMELL J; ZENG K; HEATH A; HOWARD M; HO W; DAVIS MM, 1994, 'MECHANISMS FOR ELIMINATING OR INACTIVATING SELF-REACTIVE B-CELLS', in JOURNAL OF CELLULAR BIOCHEMISTRY, WILEY-LISS, pp. 287 - 287, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1994NE25400931&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
1994
GOODNOW CC; HARTLEY SB; COOKE MP; BELL SE; SHOKAT KM; CYSTER JG; AKKARAJU S; RATHMELL J; HO W; DAVIS MM; FULCHER DA; BASTEN A; HARRIS AW; CORY S; HEATH A; LUND F; HOWARD M, 1993, 'MECHANISMS FOR ELIMINATING OR INACTIVATING SELF-REACTIVE B-CELLS', in JOURNAL OF LEUKOCYTE BIOLOGY, FEDERATION AMER SOC EXP BIOL, pp. 34 - 34, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1993ME18500009&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
1993
HARTLEY SB; COOKE MP; FULCHER D; HARRIS AW; CORY S; BASTEN A; GOODNOW CC, 1993, 'ARRESTED DEVELOPMENT AND CELL-DEATH DURING THE ELIMINATION OF SELF-REACTIVE LYMPHOCYTES-B', in JOURNAL OF CELLULAR BIOCHEMISTRY, WILEY-LISS, pp. 249 - 249, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1993KN46500897&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
1993
CYSTER JG; HARTLEY SB; GOODNOW CC, 1993, 'ARRESTED DEVELOPMENT OF IMMATURE SELF-REACTIVE B-CELLS ON ENCOUNTER WITH ANTIGEN IS REVERSED BY REMOVAL OF ANTIGEN BUT NOT BY T-CELL HELP', in JOURNAL OF LEUKOCYTE BIOLOGY, FEDERATION AMER SOC EXP BIOL, pp. 40 - 40, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1993ME18500044&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
1993
HARTLEY SB; GOODNOW CC, 1993, 'LOW-AFFINITY SELF-REACTIVE B-CELLS ARE ELIMINATED IN HEAVY-CHAIN ONLY TRANSGENIC MICE FOLLOWING ENCOUNTER WITH MEMBRANE-BOUND SELF ANTIGEN', in JOURNAL OF LEUKOCYTE BIOLOGY, FEDERATION AMER SOC EXP BIOL, pp. 93 - 93, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1993ME18500357&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
1993
SHOKAT KM; GOODNOW CC, 1993, 'ANERGIC SELF-REACTIVE B-CELLS IN THE RESPONSE TO SELF-LIKE FOREIGN ANTIGENS', in JOURNAL OF CELLULAR BIOCHEMISTRY, WILEY-LISS, pp. 251 - 251, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1993KN46500905&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
1993
BELL SE; GOODNOW CC, 1993, 'REGULATION OF SURFACE-IMMUNOGLOBULIN EXPRESSION IN TOLERANT B-CELLS', in JOURNAL OF CELLULAR BIOCHEMISTRY, WILEY-LISS, pp. 247 - 247, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1993KN46500891&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
1993
COOKE MP; ZENG K; HEATH A; LINSLEY P; HOWARD M; GOODNOW CC, 1993, 'B-CELL TOLERANCE IS MEDIATED BY ANTIGEN RECEPTOR DESENSITIZATION', in JOURNAL OF CELLULAR BIOCHEMISTRY, WILEY-LISS, pp. 248 - 248, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1993KN46500895&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
1993
Arnold B; Goodnow C; Hengartner H; Hammerling G, 1990, 'The coming of transgenic mice: Tolerance and immune reactivity', in Immunology Today, pp. 69 - 72, http://dx.doi.org/10.1016/0167-5699(90)90026-6
1990
Goodnow CC; Crosbie J; Adelstein S; Lavoie TB; Smith-Gill SJ; Mason DY; Jorgensen H; Brink RA; Pritchard-Briscoe H; Loughnan M; Loblay RH; Trent RJ; Basten A, 1989, 'Clonal silencing of self-reactive B lymphocytes in a transgenic mouse model', in Cold Spring Harbor Symposia on Quantitative Biology, pp. 907 - 920, http://dx.doi.org/10.1101/sqb.1989.054.01.106
1989
GOODNOW CC; MASON DY; LOUGHNAN M; CROSBIE J; ADELSTEIN S; JORGENSEN H; BASTEN A, 1989, 'REVERSIBILITY OF B-CELL TOLERANCE IN LYSOZYME ANTILYSOZYME TRANSGENIC MICE', in JANEWAY CA; SPRENT J; SERCARZ E (eds.), IMMUNOGENICITY, WILEY-LISS, INC, CO, STEAMBOAT, pp. 195 - 202, presented at SYMP ON IMMUNOGENICITY, CO, STEAMBOAT, 21 January 1989 - 28 January 1989, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1990BR41P00025&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
1989
BASTEN A; BRINK RA; MASON DY; CROSBIE J; GOODNOW CC, 1989, 'SELF-TOLERANCE IN B-CELLS FROM DIFFERENT LINES OF LYSOZYME DOUBLE-TRANSGENIC MICE', in MELCHERS F (ed.), PROGRESS IN IMMUNOLOGY, VOL 7, SPRINGER-VERLAG BERLIN, FED REP GER, BERLIN, pp. 377 - 384, presented at 7TH INTERNATIONAL CONGRESS OF IMMUNOLOGY, FED REP GER, BERLIN, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1989BP83Z00049&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
1989
GOODNOW CC; CROSBIE J; ADELSTEIN S; LAVOIE TB; SMITHGILL SJ; BRINK RA; PRITCHARDBRISCOE H; WOTHERSPOON JS; LOBLAY RH; RAPHAEL K; TRENT RJ; BASTEN A, 1988, 'IMMUNOLOGICAL-TOLERANCE IN LYSOZYME ANTILYSOZYME TRANSGENIC MICE', in SMITHGILL SJ; SERCARZ EE (ed.), IMMUNE RESPONSE TO STRUCTURALLY DEFINED PROTEINS : THE LYSOZYME MODEL, ADENINE PRESS, MD, MARY WOODARD LASKER CTR HLTH RES & EDUC, BETHESDA, pp. 389 - 402, presented at WORKSHOP ON THE IMMUNOLOGY OF LYSOZYME, MD, MARY WOODARD LASKER CTR HLTH RES & EDUC, BETHESDA, 13 June 1988 - 15 June 1988, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1989BR20A00037&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
1988
IVARS F; BERG L; GOODNOW C; GARCHON HJ; GILFILLAN S; DAVIS M, 1987, 'EXPRESSION OF CLONED T-CELL RECEPTOR GENES', in JOURNAL OF CELLULAR BIOCHEMISTRY, WILEY-LISS, pp. 278 - 278, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1987G822900714&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
1987
GASCOIGNE NRJ; GOODNOW C; DUDZIK K; DAVIS MM, 1987, 'SECRETION OF CHIMERIC T-CELL RECEPTOR-IMMUNOGLOBULIN FUSION PROTEINS', in JOURNAL OF CELLULAR BIOCHEMISTRY, WILEY-LISS, pp. 259 - 259, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1987G822900657&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
1987
HAYDEN GE; RAISON RL; GOODNOW CC; WALKER KZ, 1984, 'A CYTOPLASMIC DETERMINANT PRESENT IN CERTAIN TRANSFORMED OR ACTIVATED T-CELLS IS RECOGNIZED BY A MONOCLONAL-ANTIBODY TO FREE KAPPA-CHAINS', in IMMUNOBIOLOGY, GUSTAV FISCHER VERLAG, pp. 244 - 244, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1984TG29000372&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
1984
RAISON RL; WALKER KZ; HAYDEN GE; GOODNOW CC, 1984, 'TUMOR RECOGNITION AND TARGETING WITH MONOCLONAL-ANTIBODIES', in PROCEEDINGS OF THE AUSTRALIAN BIOCHEMICAL SOCIETY, PROC AUST BIOCHEMICAL SOC, pp. S27 - S27, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1984ANC4600049&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
1984
BEGHE C; GOODNOW C; REED V; FISCHER R; NICHOLAS W, 1982, 'INSULIN (I) THERAPY IN NON INSULIN DEPENDENT (NID) DIABETES-MELLITUS (DM) ASSOCIATED WITH OBESITY(O)', in CLINICAL RESEARCH, SLACK INC, pp. A917 - A917, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1982PU40600541&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
1982
Book Chapters
add
Goodnow CC; Christ D; Reed JH, 2018, 'Sequencing and affinity determination of antigen-specific B lymphocytes from peripheral blood', in Nevoltris D; Chames P (ed.), Antibody Engineering. Methods in Molecular Biology, Humana Press, New York, NY, pp. 287 - 309, http://dx.doi.org/10.1007/978-1-4939-8648-4_15
2018
Goodnow CC, 1997, 'Glimpses into the Balance Between Immunity and Self‐Tolerance', in Ciba Foundation Symposium 204 - The Molecular Basis of Cellular Defence Mechanisms, Wiley, pp. 190 - 207, http://dx.doi.org/10.1002/9780470515280.ch13
1997
Davis MM; Goodnow C; Gascoigne NRJ; Lindsten T; Chien Y, 1986, 'Murine T-Cell Receptor Genes and the Problems of Cellular Recognition and Repertoire Selection', in Regulation of Immune Gene Expression, Humana Press, pp. 137 - 142, http://dx.doi.org/10.1007/978-1-4612-5014-2_12
1986
Walker KZ; Boux HA; Hayden GE; Goodnow CC; Raison RL, 1985, 'A Monoclonal Antibody with Selectivity for Human Kappa Myeloma and Lymphoma Cells which has Potential as a Therapeutic Agent', in Microenvironments in the Lymphoid System, Springer Nature, pp. 833 - 841, http://dx.doi.org/10.1007/978-1-4613-2463-8_101
1985
Reports
add
Kumar SS; Graham GG; Smith FC; Furlong TJ; Greenfield JR; Stocker SS; Carland JE; Day RO, 2017, Could metformin be used in patients with advanced chronic kidney disease?, http://dx.doi.org/10.1111/dom.12806
2017
Shrosbree J; Pokorny A; Stone E; Epstein R; Mccormack A; Greenfield JR, 2016, Ectopic Cushing syndrome due to neuroendocrine prostatic cancer, http://dx.doi.org/10.1111/imj.13063
2016
Books
add
Papathanasiou P; Goodnow CC, 2005, Connecting mammalian genome with phenome by ENU mouse mutagenesis: Gene combinations specifying the immune system, http://dx.doi.org/10.1146/annurev.genet.39.110304.095817
2005
Cornall RJ; Goodnow CC; Cyster JG, 1999, Regulation of B cell antigen receptor signaling by the Lyn/CD22/SHP1 pathway, http://dx.doi.org/10.1007/978-3-642-58537-1_5
1999
Healy JI; Goodnow CC, 1998, Positive versus negative signaling by lymphocyte antigen receptors, http://dx.doi.org/10.1146/annurev.immunol.16.1.645
1998
|
1984 |
Honours Class I with B.V.Sc. degree; |
|
1986 |
NH & MRC Biomedical Research Scholarship |
|
1989 |
Medical Foundation Postdoctoral Fellowship |
|
1990 |
Investigator of the Howard Hughes Medical Institute |
|
1992 |
Searle Scholar |
|
1998 |
American Association of Immunologists Pharmingen Investigator Award |
|
2001 |
Gottschalk Medal, Australian Academy of Science |
|
2002 |
Fellow of the Australian Academy of Science |
|
2005 |
Health Minister’s Prize for Excellence in Medical Research |
|
2005 |
ISI Highly Cited Researcher |
|
2006 |
Centenary Medal |
|
2006 |
ARC Federation Fellow |
|
2007 |
Ramaciotti Major Research Award |
|
2009 |
Fellow of the Royal Society |
|
2010 |
NHMRC Australia Fellow |
|
2010 |
The Ramaciotti Medal |
|
2012 |
Glaxo-Smith-Kline Award for Research Excellence |
|
2013 |
Member of the US National Academy of Science |
|
2018 |
William E Paul Memorial Award, The Foundation for Primary Immune Diseases. |